Decellularization in tissue engineering and regenerative medicine: evaluation, modification, and application methods

A Neishabouri, A Soltani Khaboushan… - … in bioengineering and …, 2022‏ - frontiersin.org
Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies

KE Martin, AJ García - Acta biomaterialia, 2021‏ - Elsevier
Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021‏ - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017‏ - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

Macrophage and fibroblast interactions in biomaterial‐mediated fibrosis

CE Witherel, D Abebayehu, TH Barker… - Advanced healthcare …, 2019‏ - Wiley Online Library
Biomaterial‐mediated inflammation and fibrosis remain a prominent challenge in designing
materials to support tissue repair and regeneration. Despite the many biomaterial …

[HTML][HTML] Implant fibrosis and the underappreciated role of myofibroblasts in the foreign body reaction

N Noskovicova, B Hinz, P Pakshir - Cells, 2021‏ - mdpi.com
Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

[HTML][HTML] Abdominal wall hernia repair: from prosthetic meshes to smart materials

Q Saiding, Y Chen, J Wang, CL Pereira, B Sarmento… - Materials Today Bio, 2023‏ - Elsevier
Hernia reconstruction is one of the most frequently practiced surgical procedures worldwide.
Plastic surgery plays a pivotal role in reestablishing desired abdominal wall structure and …

Ångstrom-scale silver particle–embedded carbomer gel promotes wound healing by inhibiting bacterial colonization and inflammation

CY Chen, H Yin, X Chen, TH Chen, HM Liu, SS Rao… - Science …, 2020‏ - science.org
Poor wound healing after diabetes or extensive burn remains a challenging problem.
Recently, we presented a physical approach to fabricate ultrasmall silver particles from …

Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

ME Ogle, CE Segar, S Sridhar… - … Biology and Medicine, 2016‏ - journals.sagepub.com
Monocytes and macrophages play a critical role in tissue development, homeostasis, and
injury repair. These innate immune cells participate in guiding vascular remodeling …

Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019‏ - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …