Transdermal drug delivery via microneedles to mediate wound microenvironment

R Mo, H Zhang, Y Xu, X Wu, S Wang, Z Dong… - Advanced Drug Delivery …, 2023 - Elsevier
Cutaneous wound healing is a complex process, while modulating the wound
microenvironment has become an essential therapeutic goal. In clinics, advanced dressings …

Microneedle-based transdermal detection and sensing devices

J Wang, Z Lu, R Cai, H Zheng, J Yu, Y Zhang, Z Gu - Lab on a Chip, 2023 - pubs.rsc.org
Microneedles have been expected for the construction of next-generation biosensors
towards personalization, digitization, and intellectualization due to their metrics of minimal …

Emerging antibacterial nanozymes for wound healing

J Shan, J Che, C Song, Y Zhao - Smart Medicine, 2023 - Wiley Online Library
Wound infections continuously impose a huge economic and social burden on public
healthcare. Despite the effective treatment of bacteria‐infected wounds after using traditional …

Yunnan Baiyao-loaded multifunctional microneedle patches for rapid hemostasis and cutaneous wound healing

J Yang, X Wang, D Wu, K Yi, Y Zhao - Journal of Nanobiotechnology, 2023 - Springer
Microneedle patches have been extensively employed for wound healing, while the lack of
rapid hemostasis efficiency and multiple tissue-repair properties restrict their values in …

Nanozybiotics: advancing antimicrobial strategies through biomimetic mechanisms

C Zhou, Q Wang, H Cao, J Jiang, L Gao - Advanced Materials, 2024 - Wiley Online Library
Infectious diseases caused by bacterial, viral, and fungal pathogens present significant
global health challenges. The rapid emergence of antimicrobial resistance exacerbates this …

Smart microneedle patches for wound healing and management

F Hu, Q Gao, J Liu, W Chen, C Zheng, Q Bai… - Journal of Materials …, 2023 - pubs.rsc.org
The number of patients with non-healing wounds is generally increasing globally, placing a
huge social and economic burden on every country. The complexity of the wound-healing …

Research progress of advanced microneedle drug delivery system and its application in biomedicine

R Zhang, Q Miao, D Deng, J Wu, Y Miao, Y Li - Colloids and Surfaces B …, 2023 - Elsevier
Transdermal drug delivery is an effective way of drug delivery in addition to oral and
intravenous administration. Among them, microneedle administration is a new type of …

Spatiotemporal catalytic nanozymes microneedle patches with opposite properties for wound management

J Shan, X Zhang, L Wang, Y Zhao - Small, 2023 - Wiley Online Library
Reactive oxygen species (ROS)‐mediated biological catalysis involves serial programmed
enzymatic reactions and plays an important part against infectious diseases; while the …

Enzyme‐Like Photocatalytic Octahedral Rh/Ag2MoO4 Accelerates Diabetic Wound Healing by Photo‐Eradication of Pathogen and Relieving Wound Hypoxia

H Li, J Jiang, X Lv, Y Xu, W Wang, D Yang, X Dong - Small, 2024 - Wiley Online Library
The harsh environment of diabetic wounds, including bacterial infection and wound hypoxia,
is not conducive to wound healing. Herein, an enzyme‐like photocatalytic octahedral …

Microneedles: a novel strategy for wound management

ZQ Zhao, L Liang, LY **g, Y Liu, YH Zhang… - Biomaterials …, 2023 - pubs.rsc.org
Wound management is a serious concern worldwide, inflicting a huge social and economic
burden on patients and healthcare systems, and research into efficient wound-management …