Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …
discovered recently due to developments in understanding the human microbiota. As …
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …
the pathogenesis of disease, has been identified over the past two decades. One of the …
Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
The human intestinal microbiome in health and disease
The Human Intestinal Microbiome in Health and Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …
Skip to main content The New England Journal of Medicine homepage Advanced Search …
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
Gut microbiota, metabolites and host immunity
MG Rooks, WS Garrett - Nature reviews immunology, 2016 - nature.com
The microbiota—the collection of microorganisms that live within and on all mammals—
provides crucial signals for the development and function of the immune system. Increased …
provides crucial signals for the development and function of the immune system. Increased …
[HTML][HTML] Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
The gastrointestinal (GI) tract contains much of the body's serotonin (5-hydroxytryptamine, 5-
HT), but mechanisms controlling the metabolism of gut-derived 5-HT remain unclear. Here …
HT), but mechanisms controlling the metabolism of gut-derived 5-HT remain unclear. Here …
Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
Dysbiosis and the immune system
Throughout the past century, we have seen the emergence of a large number of
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …