Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Histone acetylation: molecular mnemonics on the chromatin

J Gräff, LH Tsai - Nature Reviews Neuroscience, 2013 - nature.com
Long-lasting memories require specific gene expression programmes that are, in part,
orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in …

BDNF and memory processing

P Bekinschtein, M Cammarota, JH Medina - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor has emerged as one of the most important molecules
involved in memory. Its wide role in different types of memories that depend on different …

Epigenetic regulation of memory formation and maintenance

IB Zovkic, MC Guzman-Karlsson… - Learning & …, 2013 - learnmem.cshlp.org
Understanding the cellular and molecular mechanisms underlying the formation and
maintenance of memories is a central goal of the neuroscience community. It is well …

Reelin and neuropsychiatric disorders

K Ishii, K Kubo, K Nakajima - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Proper neuronal migration and laminar formation during corticogenesis is essential for
normal brain function. Disruption of these developmental processes is thought to be …

Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer's disease brain

W Hong, Z Wang, W Liu, TT O'Malley, M **… - Acta …, 2018 - Springer
Significant data suggest that soluble Aβ oligomers play an important role in Alzheimer's
disease (AD), but there is great confusion over what exactly constitutes an Aβ oligomer and …

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

MJ Millan - Neuropharmacology, 2013 - Elsevier
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Running-induced epigenetic and gene expression changes in the adolescent brain

JLB Abel, EF Rissman - International Journal of Developmental …, 2013 - Elsevier
Physical exercise is associated with positive neural functioning. Here we examined the gene
expression consequences of 1 week of voluntary wheel running in adolescent male mice …

Differential methylation of genes in the medial prefrontal cortex of develo** and adult rats following exposure to maltreatment or nurturing care during infancy

J Blaze, L Scheuing, TL Roth - Developmental neuroscience, 2013 - karger.com
Quality of maternal care in infancy is an important contributing factor in the development of
behavior and psychopathology. One way maternal care could affect behavioral trajectories …

Epigenetic mechanisms of memory formation and reconsolidation

TJ Jarome, FD Lubin - Neurobiology of learning and memory, 2014 - Elsevier
Memory consolidation involves transcriptional control of genes in neurons to stabilize a
newly formed memory. Following retrieval, a once consolidated memory destabilizes and …