Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

Although surgical resection is currently the first choice of clinical treatment for most solid
tumors, postoperative cancer recurrence and metastasis are the main causes of mortality …

Inactivated virus vaccines with whole antigen spectra and good safety are the commonly
used modality for preventing infections. However, the poor immunogenicity greatly limits its …

One driver of the high failure rates of clinical trials for therapeutic cancer vaccines is likely
the inability to sufficiently engage conventional dendritic cells (cDCs), the antigen …

Immunotherapy has played an important role in the treatment of malignant tumors. Efforts in
this area are focused on exploiting a facile scaffold-based cancer vaccine with admirable …

Hydrogels, a class of materials with a 3D network structure, are widely used in various
applications of therapeutic delivery, particularly cancer therapy. Micro and nanogels as …

Following immunization, lymph nodes dynamically expand and contract. The mechanical
and cellular changes enabling the early-stage expansion of lymph nodes have been …

The impact of chirality on immune response has attracted great interest in cancer vaccine
research recently. However, the study of chiral synthetic polypeptide hydrogels as cancer …

Therapeutic cancer vaccines offer the promise of stimulating the immune system to
specifically eradicate tumor cells and establish long-term memory to prevent tumor …