Oxidative stress-induced endothelial dysfunction in cardiovascular diseases

A Shaito, K Aramouni, R Assaf, A Parenti, A Orekhov… - 2022 - qspace.qu.edu.qa
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …

Reactive oxygen species: modulators of phenotypic switch of vascular smooth muscle cells

A Badran, SA Nasser, J Mesmar, AF El-Yazbi… - International journal of …, 2020 - mdpi.com
Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At
physiological levels, they play a vital role in cell signaling. However, high ROS levels cause …

Management of endocrine disease: Optimal feminizing hormone treatment in transgender people

D Glintborg, G T'Sjoen, P Ravn… - European journal of …, 2021 - academic.oup.com
Transgender women are assigned male at birth but identified as women. The incidence of
gender dysphoria is estimated to be around 1% of the population. Gender dysphoria may be …

Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes

M Ramadan, B Cooper, NG Posnack - Birth defects research, 2020 - Wiley Online Library
Phthalates and bisphenols are high production volume chemicals that are used in the
manufacturing of consumer and medical products. Given the ubiquity of bisphenol and …

Estrogen and bisphenol A in hypertension

Z Wehbe, SA Nasser, A El-Yazbi, S Nasreddine… - Current hypertension …, 2020 - Springer
Abstract Purpose of Review Cardiovascular disease (CVD) is a non-subsiding disease that
remains a leading cause of morbidity and mortality. CVD has been associated with …

[HTML][HTML] The etiology and pathophysiology genesis of benign prostatic hyperplasia and prostate cancer: a new perspective

TJ Phua - Medicines, 2021 - mdpi.com
Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …

Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets

MM Fardoun, D Maaliki, N Halabi, R Iratni… - Clinical …, 2020 - portlandpress.com
Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in
addition to beverages such as tea and coffee. Flavonoids are emerging as potent …

The pharmaco-epigenetics of hypertension: a focus on microRNA

S Yaacoub, A Boudaka, A AlKhatib, G Pintus… - Molecular and Cellular …, 2024 - Springer
Hypertension is a major harbinger of cardiovascular morbidity and mortality. It predisposes
to higher rates of myocardial infarction, chronic kidney failure, stroke, and heart failure than …

Sex differences in cardiovascular response to sepsis

CA Shields, X Wang… - American Journal of …, 2023 - journals.physiology.org
Recently, there has been increased recognition of the importance of sex as a biological
factor affecting disease and health. Many preclinical studies have suggested that males may …

[HTML][HTML] The role of epac in cancer progression

N Wehbe, H Slika, J Mesmar, SA Nasser… - International journal of …, 2020 - mdpi.com
Cancer continues to be a prime contributor to global mortality. Despite tremendous research
efforts and major advances in cancer therapy, much remains to be learned about the …