MicroRNA regulation of atherosclerosis

MW Feinberg, KJ Moore - Circulation research, 2016 - Am Heart Assoc
Atherosclerosis and its attendant clinical complications, such as myocardial infarction,
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …

Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review

R Navickas, D Gal, A Laucevičius… - Cardiovascular …, 2016 - academic.oup.com
The aim of the present study is to identify microRNAs (miRs) with high potential to be used
as biomarkers in plasma and/or serum to clinically diagnose, or provide accurate prognosis …

Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects

C Backes, E Meese, A Keller - Molecular diagnosis & therapy, 2016 - Springer
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Non-coding RNAs in cardiovascular cell biology and atherosclerosis

F Fasolo, K Di Gregoli, L Maegdefessel… - Cardiovascular …, 2019 - academic.oup.com
Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …

Oxidative stress in ischemic heart disease

A Kibel, AM Lukinac, V Dambic, I Juric… - Oxidative medicine …, 2020 - Wiley Online Library
One of the novel interesting topics in the study of cardiovascular disease is the role of the
oxidation system, since inflammation and oxidative stress are known to lead to …

Epigenetic-sensitive pathways in personalized therapy of major cardiovascular diseases

C Schiano, G Benincasa, M Franzese… - Pharmacology & …, 2020 - Elsevier
The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

The molecular basis of predicting atherosclerotic cardiovascular disease risk

M Nayor, KJ Brown, RS Vasan - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …

Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease

J Faccini, JB Ruidavets, P Cordelier, F Martins… - Scientific reports, 2017 - nature.com
Coronary artery disease (CAD) is the most prevalent cause of mortality and morbidity
worldwide and the number of individuals at risk is increasing. To better manage …

[HTML][HTML] microRNA-based diagnostics and therapy in cardiovascular disease—Summing up the facts

C Schulte, T Zeller - Cardiovascular diagnosis and therapy, 2015 - ncbi.nlm.nih.gov
Circulating microRNAs (miRNAs) are discussed as potential disease-specific biomarkers in
cardiovascular disease. Their diagnostic value has been examined in numerous studies and …