The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

The reductive amination, the reaction of an aldehyde or a ketone with ammonia or an amine
in the presence of a reducing agent and often a catalyst, is an important amine synthesis …

Reductive aminations constitute an important class of reactions widely applied in research
laboratories and industries for the synthesis of amines as well as pharmaceuticals …

Circularly polarized luminescence (CPL) is attracting much interest because it can carry
extensive optical information. CPL shows left-or right-handedness and can be regarded as …

Efficient and general methods for the synthesis of amines remain in high demand in the
chemical industry. Among the many known processes, catalytic hydrogenation is a cost …

Chiral amine diastereomers are ubiquitous in pharmaceuticals and agrochemicals, yet their
preparation often relies on low-efficiency multi-step synthesis. These valuable compounds …

To increase the reliability and success rate of drug discovery, efforts have been made to
increase the C (sp 3) fraction and avoid flat molecules. sp 3-Rich enantiopure amines are …

Asymmetric reductive amination (ARA) of a prochiral carbonyl compound with an amine
using a H2/hydrogen surrogate is a concise and operationally simple method for the …

This Review recaps the achievements in the field of metal-catalyzed asymmetric direct
hydrogenation of nonactivated and activated imines. A summary of the reported catalytic …

Catalysis plays a decisive role in the advancement of sustainable processes in chemical,
pharmaceutical, and agrochemical industries as well as petrochemical, material, and energy …