Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …

Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

Extracellular vesicles and exomere nanoparticles are under intense investigation as sources
of clinically relevant cargo. Here we report the discovery of a distinct extracellular …

MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene
expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) …

MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

Pseudouridine is a modified nucleotide that is prevalent in human mRNAs and is
dynamically regulated. Here, we investigate when in their life cycle mRNAs become …

MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …

MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

Many proteins regulate the expression of genes by binding to specific regions encoded in
the genome 1. Here we introduce a new data set of RNA elements in the human genome …

MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …