Genipin-crosslinked chitosan gels and scaffolds for tissue engineering and regeneration of cartilage and bone

RAA Muzzarelli, M El Mehtedi, C Bottegoni, A Aquili… - Marine drugs, 2015 - mdpi.com
The present review article intends to direct attention to the technological advances made
since 2009 in the area of genipin-crosslinked chitosan (GEN-chitosan) hydrogels. After a …

Covalent layer-by-layer films: chemistry, design, and multidisciplinary applications

Q An, T Huang, F Shi - Chemical Society Reviews, 2018 - pubs.rsc.org
Covalent layer-by-layer (LbL) assembly is a powerful method used to construct functional
ultrathin films that enables nanoscopic structural precision, componential diversity, and …

Biologically inspired smart release system based on 3D bioprinted perfused scaffold for vascularized tissue regeneration

H Cui, W Zhu, B Holmes, LG Zhang - Advanced science, 2016 - Wiley Online Library
A critical challenge to the development of large‐scale artificial tissue grafts for defect
reconstruction is vascularization of the tissue construct. As an emerging tissue/organ …

Advancing bone tissue engineering one layer at a time: a layer-by-layer assembly approach to 3D bone scaffold materials

MA Sahebalzamani, M Ziminska, HO McCarthy… - Biomaterials …, 2022 - pubs.rsc.org
The layer-by-layer (LbL) assembly technique has shown excellent potential in tissue
engineering applications. The technique is mainly based on electrostatic attraction and …

Genipin: A natural blue pigment for food and health purposes

IA Neri-Numa, MG Pessoa, BN Paulino… - Trends in food science & …, 2017 - Elsevier
Natural and synthetic pigments are widely used to colour foodstuffs in order to make the
processed food more attractive to consumers (Carocho et al., 2015, Spence, 2015, Stich …

Biomimetic extracellular environment based on natural origin polyelectrolyte multilayers

JM Silva, RL Reis, JF Mano - Small, 2016 - Wiley Online Library
Surface modification of biomaterials is a well‐known approach to enable an adequate
biointerface between the implant and the surrounding tissue, dictating the initial acceptance …

Layer-by-layer assemblies of biopolymers: Build-up, mechanical stability and molecular dynamics

J Campbell, AS Vikulina - Polymers, 2020 - mdpi.com
Rapid development of versatile layer-by-layer technology has resulted in important
breakthroughs in the understanding of the nature of molecular interactions in multilayer …

Controlling cell adhesion using layer-by-layer approaches for biomedical applications

S Guo, X Zhu, XJ Loh - Materials Science and Engineering: C, 2017 - Elsevier
Controlling the adhesion of mammalian and bacterial cells at the interfaces between
synthetic materials and biological environments is a real challenge in the biomedical fields …

Layer-by-layer assembly as a robust method to construct extracellular matrix mimic surfaces to modulate cell behavior

K Ren, M Hu, H Zhang, B Li, W Lei, J Chen… - Progress in Polymer …, 2019 - Elsevier
Cellular behavior is crucially dependent on the biophysical and biochemical properties of
the extracellular matrix (ECM), in which the properties of biochemistry, topography, and …

Adhesive free-standing multilayer films containing sulfated levan for biomedical applications

TD Gomes, SG Caridade, MP Sousa, S Azevedo… - Acta biomaterialia, 2018 - Elsevier
This work is the first reporting the use of layer-by-layer to produce adhesive free-standing
(FS) films fully produced using natural-based macromolecules: chitosan (CHI), alginate …