Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the
brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately …

This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

Clinical, pathological, and imaging evidence in multiple sclerosis (MS) suggests that a
smoldering inflammatory activity is present from the earliest stages of the disease and …

The first phase of the Human Connectome Project pioneered advances in MRI technology
for map** the macroscopic structural connections of the living human brain through the …

Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

While glia are increasingly implicated in the pathophysiology of psychiatric and
neurodegenerative disorders, available methods for imaging these cells in vivo involve …

Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …