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Computational psychiatry: from synapses to sentience
This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics
Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …
response properties of neurons are dynamically modulated to support adaptive cognitive …
[HTML][HTML] Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however,
the underlying mechanisms are unclear. Despite a well-documented association between …
the underlying mechanisms are unclear. Despite a well-documented association between …
How do expectations shape perception?
Perception and perceptual decision-making are strongly facilitated by prior knowledge about
the probabilistic structure of the world. While the computational benefits of using prior …
the probabilistic structure of the world. While the computational benefits of using prior …
[HTML][HTML] The predictive coding account of psychosis
Fueled by developments in computational neuroscience, there has been increasing interest
in the underlying neurocomputational mechanisms of psychosis. One successful approach …
in the underlying neurocomputational mechanisms of psychosis. One successful approach …
Active interoceptive inference and the emotional brain
We review a recent shift in conceptions of interoception and its relationship to hierarchical
inference in the brain. The notion of interoceptive inference means that bodily states are …
inference in the brain. The notion of interoceptive inference means that bodily states are …
Functional neuroimaging in psychiatry and the case for failing better
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …
among the most debilitating and poorly understood of any medical condition. Current …
[HTML][HTML] Active inference on discrete state-spaces: A synthesis
Active inference is a normative principle underwriting perception, action, planning, decision-
making and learning in biological or artificial agents. From its inception, its associated …
making and learning in biological or artificial agents. From its inception, its associated …
Adults with autism overestimate the volatility of the sensory environment
Insistence on sameness and intolerance of change are among the diagnostic criteria for
autism spectrum disorder (ASD), but little research has addressed how people with ASD …
autism spectrum disorder (ASD), but little research has addressed how people with ASD …
The empirical status of predictive coding and active inference
Research on predictive processing models has focused largely on two specific algorithmic
theories: Predictive Coding for perception and Active Inference for decision-making. While …
theories: Predictive Coding for perception and Active Inference for decision-making. While …