Simple Summary Over 500,000 individuals died due to esophageal cancer (EC) worldwide
in 2020. More than four decades of etiological research have predominantly focused on the …

Discriminating the contribution of unmodifiable random intrinsic DNA replication errors ('bad
luck') to cancer development from those of other factors is critical for understanding cancer in …

Largely due to population ageing, the cancer burden from older people has been rising,
which imposed considerable pressure on current Chinese healthcare system. We provide …

INTRODUCTION Cancer genome studies have contributed to the analysis and discovery of
somatic mutations that drive cancer growth. However, studying the genetic makeup of a …

There are limited published data on recent cancer incidence and mortality trends worldwide.
We used the International Agency for Research on Cancer's CANCER Mondial …

Cancer is a life-threatening disease caused by the uncontrolled division of cells, which
culminates in a solid mass of cells known as a tumor or liquid cancer. It is the leading cause …

Background Oesophageal cancer is a common and often fatal cancer that has two main
histological subtypes: oesophageal squamous cell carcinoma and oesophageal …

Recent research has highlighted a strong correlation between tissue-specific cancer risk
and the lifetime number of tissue-specific stem-cell divisions. Whether such correlation …

The global burden of cancer continues to increase largely because of the aging and growth
of the world population alongside an increasing adoption of cancer‐causing behaviors …

Esophageal cancer (EC) is the seventh most common cancer worldwide with over 570,000
new cases annually. In China, the incidence of EC is particularly high where approximately …