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Fast-spiking parvalbumin-positive interneurons in brain physiology and Alzheimer's disease
Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …
morphological and functional properties that allow them to precisely control local circuitry …
Neuronal circuits for fear and anxiety
Decades of research has identified the brain areas that are involved in fear, fear extinction,
anxiety and related defensive behaviours. Newly developed genetic and viral tools …
anxiety and related defensive behaviours. Newly developed genetic and viral tools …
The molecular cytoarchitecture of the adult mouse brain
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …
diversely specialized cell types. Yet, the molecular identities of the cell types and their …
[HTML][HTML] Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of
genetic markers and single-cell transcriptomics can provide insights into behavior …
genetic markers and single-cell transcriptomics can provide insights into behavior …
[HTML][HTML] Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory
Memory encodes past experiences, thereby enabling future plans. The basolateral
amygdala is a centre of salience networks that underlie emotional experiences and thus has …
amygdala is a centre of salience networks that underlie emotional experiences and thus has …
AAV-mediated anterograde transsynaptic tagging: map** corticocollicular input-defined neural pathways for defense behaviors
To decipher neural circuits underlying brain functions, viral tracers are widely applied to map
input and output connectivity of neuronal populations. Despite the successful application of …
input and output connectivity of neuronal populations. Despite the successful application of …
Optogenetics: 10 years of microbial opsins in neuroscience
Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light …
modular genetic methods for cell-type targeting and optical strategies for guiding light …
Midbrain circuits for defensive behaviour
Survival in threatening situations depends on the selection and rapid execution of an
appropriate active or passive defensive response, yet the underlying brain circuitry is not …
appropriate active or passive defensive response, yet the underlying brain circuitry is not …
From circuits to behaviour in the amygdala
The amygdala has long been associated with emotion and motivation, playing an essential
part in processing both fearful and rewarding environmental stimuli. How can a single …
part in processing both fearful and rewarding environmental stimuli. How can a single …
[HTML][HTML] Prediction and memory: A predictive coding account
The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …