Research on the origin of life is highly heterogeneous. After a peculiar historical
development, it still includes strongly opposed views which potentially hinder progress. In …

The evolution of life from the prebiotic environment required a gradual process of chemical
evolution towards greater molecular complexity. Elaborate prebiotically relevant synthetic …

“The Lipid World” was published in 2001, stemming from a highly effective collaboration with
David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in …

The burial of organic carbon, which prevents its remineralization via oxygen-consuming
processes, is considered one of the causes of Earth's oxygenation. Yet, higher levels of …

A quantitative understanding of the thermodynamics of biochemical reactions is essential for
accurately modeling metabolism. The group contribution method (GCM) is one of the most …

Carbon is a ubiquitous element in society as a critical component of materials, medicines,
commodity chemicals, and fuels. A primary reason for the broad utility of carbon-containing …

Understanding the aqueous speciation of molecular metal-oxo-clusters plays a key role in
different fields such as catalysis, electrochemistry, nuclear waste recycling, and …

Preserving human and environmental health requires anthropogenic pollutants to be
biologically degradable. Depending on concentration, both nutrients and pollutants induce …

Coenzymes distribute a variety of chemical moieties throughout cellular metabolism,
participating in group (eg, phosphate and acyl) and electron transfer. For a variety of …

A major unresolved question in the origin of life is whether there exists a continuous path
from geochemical precursors to the majority of molecules in the biosphere, due in part to the …