Mechanisms of autoantibody-induced pathology
Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …
Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is
characterized by the concomitant occurrence of often severe thrombocytopenia …
characterized by the concomitant occurrence of often severe thrombocytopenia …
An international consensus approach to the management of atypical hemolytic uremic syndrome in children
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease
largely of complement dysregulation. This advance facilitated the development of novel …
largely of complement dysregulation. This advance facilitated the development of novel …
HUS and atypical HUS
TS Jokiranta - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by
intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually …
intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually …
STEC-HUS, atypical HUS and TTP are all diseases of complement activation
Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are
diseases characterized by microvascular thrombosis, with consequent thrombocytopaenia …
diseases characterized by microvascular thrombosis, with consequent thrombocytopaenia …
Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
In the past decade, a large body of evidence has accumulated in support of the critical role
of dysregulation of the alternative complement pathway in atypical haemolytic uraemic …
of dysregulation of the alternative complement pathway in atypical haemolytic uraemic …
How I treat refractory thrombotic thrombocytopenic purpura
FA Sayani, CS Abrams - Blood, The Journal of the American …, 2015 - ashpublications.org
Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia
and microangiopathic hemolytic anemia (MAHA) without an obvious cause, and may include …
and microangiopathic hemolytic anemia (MAHA) without an obvious cause, and may include …
Brain histopathology in patients with systemic lupus erythematosus: identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of …
Objectives. Neuropsychiatric (NP) involvement is a poorly understood manifestation of SLE.
We studied post-mortem histopathology in relation to clinical NPSLE syndromes and …
We studied post-mortem histopathology in relation to clinical NPSLE syndromes and …
Update on hemolytic uremic syndrome: Diagnostic and therapeutic recommendations
M Salvadori, E Bertoni - World journal of nephrology, 2013 - pmc.ncbi.nlm.nih.gov
Hemolytic uremic syndrome (HUS) is a rare disease. In this work the authors review the
recent findings on HUS, considering the different etiologic and pathogenetic classifications …
recent findings on HUS, considering the different etiologic and pathogenetic classifications …
Spectrum of complement-mediated thrombotic microangiopathies: pathogenetic insights identifying novel treatment approaches
Thrombotic microangiopathy (TMA) is a rare but severe disorder characterized by
endothelial cell activation and thrombus formation. It manifests with the triad of hemolytic …
endothelial cell activation and thrombus formation. It manifests with the triad of hemolytic …