The various non-standard schedules required of shift workers force abrupt changes in the
timing of sleep and light-dark exposure. These changes result in disturbances of the …

This review summarises the literature on shift work and its relation to insufficient sleep,
chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic …

Most animals alternate periods of feeding with periods of fasting often coinciding with sleep.
Upon> 24 hr of fasting, humans, rodents, and other mammals enter alternative metabolic …

Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …

Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This
increased risk cannot be fully explained by classic risk factors. One of the key features of …

The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Disrupted circadian rhythms have been linked to an increased risk of hypertension and
cardiovascular disease. However, many studies show inconsistent findings and are not …

Cortisol and inflammatory proteins are released into the blood in response to stressors and
chronic elevations of blood cortisol and inflammatory proteins may contribute to ongoing …

Most organisms display endogenously produced∼ 24-hour fluctuations in physiology and
behavior, termed circadian rhythms. Circadian rhythms are driven by a transcriptional …

Shift work, defined as work occurring outside typical daytime working hours, is associated
with an increased risk of various non‐communicable diseases, including diabetes and …