Background Two randomised trials assessing the effectiveness of decompressive
craniectomy (DC) following traumatic brain injury (TBI) were published in recent years …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Background The indications for intracranial pressure (ICP) monitoring in patients with acute
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …

Background The effect of decompressive craniectomy on clinical outcomes in patients with
refractory traumatic intracranial hypertension remains unclear. Methods From 2004 through …

Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we
demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause …

Objectives: We have sought to develop an automated methodology for the continuous
updating of optimal cerebral perfusion pressure (CPP opt) for patients after severe traumatic …

Background The invasive nature of the current methods for monitoring of intracranial
pressure (ICP) has prevented their use in many clinical situations. Several attempts have …

Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …

Background Although placement of an intra-cerebral catheter remains the gold standard
method for measuring intracranial pressure (ICP), several non-invasive techniques can …

Traumatic brain injury (TBI) has been called the 'silent epidemic'of modern times, and is the
leading cause of mortality and morbidity in children and young adults in both developed and …