Abnormal synaptic pruning during adolescence underlying the development of psychotic disorders

M Germann, SG Brederoo… - Current opinion in …, 2021 - journals.lww.com
Recent findings render the pruning machinery a potential target for early treatment and
prevention in individuals at high risk for SCZ. Minocycline can improve cognition in SCZ …

Functional brain network dysfunctions in subjects at high-risk for psychosis: a meta-analysis of resting-state functional connectivity

L Del Fabro, A Schmidt, L Fortea, G Delvecchio… - Neuroscience & …, 2021 - Elsevier
Although emerging evidence suggests that altered functional connectivity (FC) of large-scale
neural networks is associated with disturbances in individuals at high-risk for psychosis, the …

Transcriptional signatures of the whole-brain voxel-wise resting-state functional network centrality alterations in schizophrenia

L Guo, J Ma, M Cai, M Zhang, Q Xu, H Wang, Y Zhang… - Schizophrenia, 2023 - nature.com
Neuroimaging studies have revealed that patients with schizophrenia exhibit disrupted
resting-state functional connectivity. However, the inconsistent findings across these studies …

Spontaneous brain activity alterations in first-episode psychosis: a meta-analysis of functional Magnetic Resonance Imaging studies

G Cattarinussi, DA Grimaldi… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis Several studies have shown that spontaneous brain
activity, including the total and fractional amplitude of low-frequency fluctuations (LFF) and …

An insula-based network mediates the relation between rumination and interoceptive sensibility in the healthy population

X Li, F Qin, J Liu, Q Luo, Y Zhang, J Hu, Y Chen… - Journal of Affective …, 2022 - Elsevier
Background Individuals sometimes continuously centered their attention on the same
thoughts. When such process tends to be negative and self-referential, we delineated this …

Static and Dynamic Dysconnectivity in Early Psychosis: Relationship With Symptom Dimensions

G Cattarinussi, DA Grimaldi, MH Aarabi… - Schizophrenia …, 2025 - academic.oup.com
Abstract Background and Hypothesis Altered functional connectivity (FC) has been
frequently reported in psychosis. Studying FC and its time-varying patterns in early-stage …

Aberrant resting-state functional brain connectivity of insular subregions in obstructive sleep apnea

L Kong, H Li, Y Shu, X Liu, P Li, K Li, W **e… - Frontiers in …, 2022 - frontiersin.org
The insular cortex is a cortical regulatory area involved in dyspnea, cognition, emotion, and
sensorimotor function. Previous studies reported that obstructive sleep apnea (OSA) shows …

Functional connectivity changes in the insular subregions of patients with obstructive sleep apnea after 6 months of continuous positive airway pressure treatment

T Long, H Li, Y Shu, K Li, W **e, Y Zeng… - Neural …, 2023 - Wiley Online Library
This study was aimed at investigating the functional connectivity (FC) changes between the
insular subregions and whole brain in patients with obstructive sleep apnea (OSA) after 6 …

[HTML][HTML] The role of the insula in cognitive impairment of schizophrenia

S Gebhardt, HA Nasrallah - Schizophrenia Research: Cognition, 2023 - Elsevier
Cognitive impairment is one of the core clinical symptom domains of schizophrenia.
Research shows that cognitive deficits in this neuropsychiatric syndrome is associated with …