Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours
are known as tumour-associated macrophages (TAMs). These specialized immune cells …

Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Tumor-associated macrophages (TAMs) are pivotal in cancer progression, influencing tumor
growth, angiogenesis, and immune evasion. This review explores the spatial and temporal …

Identifying spatially variable genes (SVGs) is crucial for understanding the spatiotemporal
characteristics of diseases and tissue structures, posing a distinctive challenge in spatial …

Аbstract With increasing incidence and geography, cancer is one of the leading causes of
death, reduced quality of life and disability worldwide. Principal progress in the development …

Breast cancer is one of the most common malignant tumors in women worldwide, and thus, it
is important to enhance its treatment efficacy [1]. Copper has emerged as a critical trace …

Macrophages represent an immune cell population characterized by high plasticity and a
range of properties and functions. Their activation status and specific phenotype are highly …

Cancer stem cells (CSCs) represent a small yet pivotal subset of tumor cells endowed with
self-renewal capabilities. These cells are intricately linked to tumor progression and are …

Chimeric antigen receptor (CAR) T cell therapy, which targets tumors with high specificity
through the recognition of particular antigens, has emerged as one of the most rapidly …