Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research

NL Benowitz, ML Goniewicz… - The Lancet …, 2022 - thelancet.com
Heterogeneity in the clinical presentation of SARS-CoV-2 infection and COVID-19
progression underscores the urgent need to identify individual-level susceptibility factors …

Cardiovascular injury induced by tobacco products: assessment of risk factors and biomarkers of harm. A Tobacco Centers of Regulatory Science compilation

DJ Conklin, S Schick, MJ Blaha… - American Journal …, 2019 - journals.physiology.org
Although substantial evidence shows that smoking is positively and robustly associated with
cardiovascular disease (CVD), the CVD risk associated with the use of new and emerging …

E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice

AP Carll, C Arab, R Salatini, MD Miles… - Nature …, 2022 - nature.com
E-cigarette use has surged, but the long-term health effects remain unknown. E-cigarette
aerosols containing nicotine and acrolein, a combustion and e-cigarette byproduct, may …

Electronic cigarette-generated aldehydes: the contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of …

DJ Conklin, MA Ogunwale, Y Chen… - Aerosol Science and …, 2018 - Taylor & Francis
Electronic cigarettes (e-cigarette) have emerged as a popular electronic nicotine delivery
system (ENDS) in the last decade. Despite the absence of combustion products and toxins …

Electronic cigarette solvents, pulmonary irritation, and endothelial dysfunction: role of acetaldehyde and formaldehyde

L **, J Lynch, A Richardson… - American Journal …, 2021 - journals.physiology.org
After more than a decade of electronic cigarette (E-cig) use in the United States, uncertainty
persists regarding E-cig use and long-term cardiopulmonary disease risk. As all E-cigs use …

Increased serum levels of aldehydes are associated with cardiovascular disease and cardiovascular risk factors in adults

C Xu, J Liang, S Xu, Q Liu, J Xu, A Gu - Journal of Hazardous Materials, 2020 - Elsevier
Previous studies have identified several genetic and environmental risk factors for
cardiovascular disease (CVD), but little is known about the associations between serum …

Investigating aldehyde and ketone compounds produced from indoor cooking emissions and assessing their health risk to human beings

W Zhang, Z Bai, L Shi, JH Son, L Li, L Wang… - Journal of Environmental …, 2023 - Elsevier
Aldehyde and ketone compounds are ubiquitous in the air and prone to adverse effects on
human health. Cooking emission is one of the major indoor sources. Aiming to evaluate …

[HTML][HTML] Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

M Sauerland, R Mertes, C Morozzi, AL Eggler… - Free Radical Biology …, 2021 - Elsevier
Humans have extensive adverse exposure to alpha, beta-unsaturated carbonyl compounds
(ABuCs) as these are major toxins in smoke and exhaust fumes, as well as products of lipid …

Mechanisms behind the atherothrombotic effects of acrolein, a review

MR Zirak, S Mehri, A Karimani, M Zeinali… - Food and Chemical …, 2019 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The majority of
cardiovascular complications are secondary to atherosclerosis. Extensive evidence has …

Environmental exposure to volatile organic compounds is associated with endothelial injury

DW Riggs, MV Malovichko, H Gao, KE McGraw… - Toxicology and applied …, 2022 - Elsevier
Abstract Objective Volatile organic compounds (VOCs) are airborne toxicants abundant in
outdoor and indoor air. High levels of VOCs are also present at various Superfund and other …