Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi, M Nader - Pharmacological Reviews, 2021 - Elsevier
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder

AL Mahan, KJ Ressler - Trends in neurosciences, 2012 - cell.com
Posttraumatic stress disorder (PTSD) is an anxiety disorder that can develop after a
traumatic experience such as domestic violence, natural disasters or combat-related trauma …

[PDF][PDF] The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies

J Pilc - Journal of physiology and pharmacology, 2010 - academia.edu
It is well documented that physical activity can induce a number of various stimuli which are
able to enhance the strength and endurance performance of muscles. Moreover, regular …

Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder

TL Roth, PR Zoladz, JD Sweatt, DM Diamond - Journal of psychiatric …, 2011 - Elsevier
Epigenetic alterations of the brain-derived neurotrophic factor (Bdnf) gene have been linked
with memory, stress, and neuropsychiatric disorders. Here we examined whether there was …

Brain-Derived Neurotrophic Factor (BDNF) protein levels in anxiety disorders: systematic review and meta-regression analysis

S Suliman, SMJ Hemmings, S Seedat - Frontiers in integrative …, 2013 - frontiersin.org
Background: Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that is involved in
the synaptic plasticity and survival of neurons. BDNF is believed to be involved in the …

Fear extinction and BDNF: translating animal models of PTSD to the clinic

R Andero, KJ Ressler - Genes, Brain and Behavior, 2012 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is the most studied neurotrophin involved in
synaptic plasticity processes that are required for long‐term learning and memory …

Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress

E Unternaehrer, P Luers, J Mill, E Dempster… - Translational …, 2012 - nature.com
Environmentally induced epigenetic alterations are related to mental health. We investigated
quantitative DNA methylation status before and after an acute psychosocial stressor in two …

Traumatic brain injury in intimate partner violence: A critical review of outcomes and mechanisms

LE Kwako, N Glass, J Campbell… - … Violence, & Abuse, 2011 - journals.sagepub.com
The prevalence of intimate partner violence (IPV) is striking, as are its consequences to the
lives of women. The IPV often includes physical assault, which can include injuries to the …

Circulating brain-derived neurotrophic factor as a potential biomarker in stroke: a systematic review and meta-analysis

H Mojtabavi, Z Shaka, S Momtazmanesh… - Journal of Translational …, 2022 - Springer
Background Stroke, an acute cerebrovascular event, is a leading cause of disability, placing
a significant psycho-socioeconomic burden worldwide. The adaptation and reorganization …

Synaptic loss and the pathophysiology of PTSD: implications for ketamine as a prototype novel therapeutic

JH Krystal, CG Abdallah, LA Averill, B Kelmendi… - Current psychiatry …, 2017 - Springer
Abstract Purpose of Review Studies of the neurobiology and treatment of PTSD have
highlighted many aspects of the pathophysiology of this disorder that might be relevant to …