ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in
Chinese people in December 2019 and has currently spread worldwide causing the COVID …
Chinese people in December 2019 and has currently spread worldwide causing the COVID …
Abdominal aortic aneurysm: update on pathogenesis and medical treatments
J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …
Immune and inflammatory mechanisms of abdominal aortic aneurysm
AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …
mediated infiltration and a destruction of the aortic wall during AAA development plays …
Renin-angiotensin system and cardiovascular functions
CH Wu, S Mohammadmoradi, JZ Chen… - … , and vascular biology, 2018 - Am Heart Assoc
Wu et al The RAS and Cardiovascular Functions e109 homocysteine decreased
antihypertensive effect of enalapril, an ACE inhibitor, in chronic hypertensive patients. 61 …
antihypertensive effect of enalapril, an ACE inhibitor, in chronic hypertensive patients. 61 …
Modulation of immune‐inflammatory responses in abdominal aortic aneurysm: Emerging molecular targets
H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …
degenerative process of the abdominal aorta. In this process, inflammatory responses and …
Mouse models for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Twenty years of studying AngII (angiotensin II)-induced abdominal aortic pathologies in mice: continuing questions and challenges to provide insight into the human …
AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
Eosinophils Protect Mice From Angiotensin-II Perfusion–Induced Abdominal Aortic Aneurysm
Rationale: Blood eosinophil count and ECP (eosinophil cationic protein) associate with
human cardiovascular diseases. Yet, whether eosinophils play a role in cardiovascular …
human cardiovascular diseases. Yet, whether eosinophils play a role in cardiovascular …
Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
L Boytard, T Hadi, M Silvestro, H Qu… - Nature …, 2020 - nature.com
Pulmonary disease increases the risk of develo** abdominal aortic aneurysms (AAA).
However, the mechanism underlying the pathological dialogue between the lungs and aorta …
However, the mechanism underlying the pathological dialogue between the lungs and aorta …
Differential roles of eosinophils in cardiovascular disease
Eosinophils are essential innate immune cells in allergic responses. Accumulating evidence
indicates that eosinophils also participate in the pathogenesis of cardiovascular diseases …
indicates that eosinophils also participate in the pathogenesis of cardiovascular diseases …