Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling
Highlights•Traditional drug screening model systems are inadequate.•Organoid-on-a-chip
platforms stand to significantly advance drug and toxicology screening.•A wide variety or …
platforms stand to significantly advance drug and toxicology screening.•A wide variety or …
The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …
produced and used in many commercial products, which could lead to the contact of human …
Organ-on-a-chip platforms for studying drug delivery systems
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems.
Organ-on-a-chip systems—microscale recapitulations of complex organ functions—promise …
Organ-on-a-chip systems—microscale recapitulations of complex organ functions—promise …
Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research
The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …
of both academic and industrial applications such as rapid genome sequencing, predictive …
[HTML][HTML] Organ-on-a-chip platforms for accelerating the evaluation of nanomedicine
Nanomedicine involves the use of engineered nanoscale materials in an extensive range of
diagnostic and therapeutic applications and can be applied to the treatment of many …
diagnostic and therapeutic applications and can be applied to the treatment of many …
Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro–in vivo gap
The number of newly engineered nanomaterials is vastly increasing along with their
applications. Despite the fact that there is a lot of interest and effort is being put into the …
applications. Despite the fact that there is a lot of interest and effort is being put into the …
Microscopy based methods for characterization, drug delivery, and understanding the dynamics of nanoparticles
Nanomedicine is an emerging field that exploits nanotechnology for the development of
novel therapeutic and diagnostic modalities. Researches are been focussed in nanoimaging …
novel therapeutic and diagnostic modalities. Researches are been focussed in nanoimaging …
Targeting drug delivery in the vascular system: Focus on endothelium
The bloodstream is the main transporting pathway for drug delivery systems (DDS) from the
site of administration to the intended site of action. In many cases, components of the …
site of administration to the intended site of action. In many cases, components of the …
Organ-on-a-chip technology for nanoparticle research
The last two decades have witnessed explosive growth in the field of nanoengineering and
nanomedicine. In particular, engineered nanoparticles have garnered great attention due to …
nanomedicine. In particular, engineered nanoparticles have garnered great attention due to …
Strategies for delivering nanoparticles across tumor blood vessels
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …