[HTML][HTML] Sex-specific differences in glioblastoma

A Carrano, JJ Juarez, D Incontri, A Ibarra, HG Cazares - Cells, 2021 - mdpi.com
Sex differences have been well identified in many brain tumors. Even though glioblastoma
(GBM) is the most common primary malignant brain tumor in adults and has the worst …

Tumor infiltrating immune cells in gliomas and meningiomas

P Domingues, M González-Tablas, Á Otero… - Brain, behavior, and …, 2016 - Elsevier
Tumor-infiltrating immune cells are part of a complex microenvironment that promotes and/or
regulates tumor development and growth. Depending on the type of cells and their …

[HTML][HTML] Different T-cell subsets in glioblastoma multiforme and targeted immunotherapy

H Wang, H Zhou, J Xu, Y Lu, X Ji, Y Yao, H Chao… - Cancer Letters, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a brain tumor with a high mortality rate. Surgical resection
combined with radiotherapy and chemotherapy is the standard treatment for GBM patients …

Cytokine patterns in brain tumour progression

R Albulescu, E Codrici, ID Popescu… - Mediators of …, 2013 - Wiley Online Library
Inflammation represents the immune system response to external or internal aggressors
such as injury or infection in certain tissues. The body's response to cancer has many …

IL-10 in glioma

SS Widodo, M Dinevska, LM Furst, SS Stylli… - British journal of …, 2021 - nature.com
The prognosis for patients with glioblastoma (GBM), the most common and malignant type of
primary brain tumour, is very poor, despite current standard treatments such as surgery …

Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers

M Prosniak, LA Harshyne, DW Andrews… - Clinical cancer …, 2013 - aacrjournals.org
Purpose: This study is directed at identifying the cell source (s) of immunomodulatory
cytokines in high-grade gliomas and establishing whether the analysis of associated …

Systemic and local immunosuppression in glioblastoma and its prognostic significance

AA Stepanenko, AO Sosnovtseva, MP Valikhov… - Frontiers in …, 2024 - frontiersin.org
The effectiveness of tumor therapy, especially immunotherapy and oncolytic virotherapy,
critically depends on the activity of the host immune cells. However, various local and …

[HTML][HTML] Cytokine profile in development of glioblastoma in relation to healthy individuals

P Jarmuzek, P Defort, M Kot… - International Journal of …, 2023 - mdpi.com
Cytokines play an essential role in the control of tumor cell development and multiplication.
However, the available literature provides ambiguous data on the involvement of these …

Cellular and molecular features related to exceptional therapy response and extreme long‐term survival in glioblastoma

B Decraene, M Vanmechelen, P Clement… - Cancer …, 2023 - Wiley Online Library
Glioblastoma Multiforme (GBM) remains the most common malignant primary brain tumor
with a dismal prognosis that rarely exceeds beyond 2 years despite extensive therapy …

[PDF][PDF] Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment

ET Ha, JP Antonios, H Soto, RM Prins… - Neuroimmunology …, 2014 - researchgate.net
This review examines glioma disease initiation, promotion, and progression with a focus on
the cell types present within the tumor mass and the molecules responsible for the …