Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Porous structure is an important three-dimensional morphological feature of the peripheral
nerve guidance conduit (NGC), which permits the infiltration of cells, nutrients, and …

Growth factors (GFs) are soluble proteins secreted by cells that have the ability to regulate a
variety of cellular processes and tissue regeneration. However, their translation into clinical …

Nerve regeneration after injury is a critical medical issue. In previous work, we have
developed an oligo (poly (ethylene glycol) fumarate)(OPF) hydrogel incorporated with …

The scaffolding biomaterials and their internal structures are crucial in constructing growth-
permissive microenvironment for tissue regeneration. A functional bioscaffold not only …

In the human body, cells in a tissue are exposed to signals derived from their specific
extracellular matrix (ECM), such as architectural structure, mechanical properties, and …

Although numerous strategies have been implemented to develop nerve guidance conduits
(NGCs) to treat peripheral nerve injury (PNI), functionalization of an NGC to make it remotely …

Biochemical and physical guidance cues are both pivotal for axonal guidance and nerve
regeneration. However, fabrication of a platform that can integrate biochemical gradients …

Conduits that promote nerve regeneration are currently of great medical concern,
particularly when gaps exist between nerve endings. To address this issue, our laboratory …

Proteins are biological macromolecules involved in a wide range of biological functions,
which makes them very appealing as therapeutics agents. Indeed, compared to small …