[HTML][HTML] Current insights and progress in the clinical management of head and neck cancer

MN Amaral, P Faísca, HA Ferreira, MM Gaspar… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer (HNC) incidence has been steadily increasing
since the 1990s. While the multimodal treatment approach for localized HNC is well …

[HTML][HTML] Immunotherapy for the treatment of squamous cell carcinoma: potential benefits and challenges

TM Ansary, MDR Hossain, M Komine… - International Journal of …, 2022 - mdpi.com
Melanoma and nonmelanoma skin cancers (NMSCs) are recognized as among the most
common neoplasms, mostly in white people, with an increasing incidence rate. Among the …

Map** the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironment

N Jhaveri, B Ben Cheikh, N Nikulina, N Ma… - GEN …, 2023 - liebertpub.com
Head and neck squamous cell carcinomas (HNSCCs) are the seventh most common cancer
and represent a global health burden. Immune checkpoint inhibitors (ICIs) have shown …

Multimodality treatment in recurrent/metastatic squamous cell carcinoma of head and neck: current therapy, challenges, and future perspectives

S Pannunzio, A Di Bello, D Occhipinti, A Scala… - Frontiers in …, 2024 - frontiersin.org
Squamous cell carcinoma of the head and neck is a complex group of diseases that
presents a challenge to the clinician. The prognosis in the recurrent/metastatic disease is …

Stereotactic body radiotherapy for extracranial oligometastatic disease from head and neck primary cancers: a systematic review and meta-analysis

A Mutsaers, A Akingbade, AV Louie, B Id Said, L Zhang… - Cancers, 2024 - mdpi.com
Simple Summary Question: Is stereotactic body radiation therapy an effective and safe
treatment option for patients with oligometastatic cancer from a head and neck primary …

[HTML][HTML] Penpulimab combined with anlotinib in patients with R/M HNSCC after failure of platinum-based chemotherapy: a single-arm, multicenter, phase Ⅱ study

Y Shi, L Gao, Y Tian, C Bai, J Chen, J Wang, X Li… - ESMO open, 2023 - Elsevier
Background Treatment regimens for recurrent or metastatic head and neck squamous cell
carcinoma (R/M HNSCC) after failure of platinum-based chemotherapy have been illustrated …

Mechanisms of resistance and therapeutic perspectives in immunotherapy for advanced head and neck cancers

A Meci, N Goyal, G Slonimsky - Cancers, 2024 - mdpi.com
Simple Summary The programmed death-1 receptor monoclonal antibody treatments
pembrolizumab and nivolumab have been successful in the treatment of recurrent or …

[HTML][HTML] Gold nanoparticles enhance the tumor growth-suppressing effects of cetuximab and radiotherapy in head and neck cancer in vitro and in vivo

T Sato, Y Kakei, T Hasegawa, M Kashin, S Teraoka… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) treatment includes
surgery, radiotherapy, and immunotherapy with the aim of eradicating cancer cells without …

[HTML][HTML] Identification of the PROMs used to assess ICI toxicities and HRQoL in patients receiving immune checkpoint inhibitor treatment in cancer care and their …

S Georgopoulou, J Droney, PP Jaganathan… - Cancer Treatment …, 2024 - Elsevier
Background The implementation of patient-reported outcome measures (PROMs) in the
clinical identification of immunotherapy toxicities is a complex intervention. There has been …

Association of neoadjuvant pembrolizumab for oral cavity squamous cell carcinoma with adverse events after surgery in treatment-naive patients

AL Tang, T O'Neil, S McDermott… - … –Head & Neck …, 2022 - jamanetwork.com
Importance Pembrolizumab, a monoclonal antibody targeting programmed cell death 1, is
currently approved by the US Food and Drug Administration for recurrent or metastatic head …