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Bioactivities and mechanisms of action of sinomenine and its derivatives: a comprehensive review
Sinomenine, an isoquinoline alkaloid extracted from the roots and stems of Sinomenium
acutum, has been extensively studied for its derivatives as bioactive agents. This review …
acutum, has been extensively studied for its derivatives as bioactive agents. This review …
Review of possible mechanisms of radiotherapy resistance in cervical cancer
H Zhang, X Wang, Y Ma, Q Zhang, R Liu, H Luo… - Frontiers in …, 2023 - frontiersin.org
Radiotherapy is one of the main treatments for cervical cancer. Early cervical cancer is
usually considered postoperative radiotherapy alone. Radiotherapy combined with cisplatin …
usually considered postoperative radiotherapy alone. Radiotherapy combined with cisplatin …
Aldolase A promotes cervical cancer cell radioresistance by regulating the glycolysis and DNA damage after irradiation
J Zhou, N Lei, B Qin, M Chen, S Gong… - Cancer Biology & …, 2023 - Taylor & Francis
Radioresistance is the major obstacle that affects the efficacy of radiotherapy which is an
important treatment for cervical cancer. By analyzing the databases, we found that aldolase …
important treatment for cervical cancer. By analyzing the databases, we found that aldolase …
From mundane to classic: Sinomenine as a multi‐therapeutic agent
Sinomenine is an active substance extracted from the traditional Chinese medicine
Sinomenium acutum. Sinomenine has been shown to mediate a wide range of …
Sinomenium acutum. Sinomenine has been shown to mediate a wide range of …
Recent progress of the tumor microenvironmental metabolism in cervical cancer radioresistance
J Zhou, N Lei, W Tian, R Guo, M Chen, L Qiu… - Frontiers in …, 2022 - frontiersin.org
Radiotherapy is widely used as an indispensable treatment option for cervical cancer
patients. However, radioresistance always occurs and has become a big obstacle to …
patients. However, radioresistance always occurs and has become a big obstacle to …
Curcumol β-cyclodextrin inclusion complex enhances radiosensitivity of esophageal cancer under hypoxic and normoxic condition
M Su, X Ren, D Du, H He, D Zhang, R **e… - Japanese Journal of …, 2023 - Springer
Purpose Radiotherapy is an indispensable treatment for esophageal cancer (EC), but
radioresistance is not uncommon. Curcumol, as an active extract from traditional Chinese …
radioresistance is not uncommon. Curcumol, as an active extract from traditional Chinese …
Mechanism underlying antitumor effects of sinomenine
L Gao, B Zhong, Y Wang - Chinese journal of integrative medicine, 2019 - Springer
Sinomenine (SIN) is a bioactive alkaloid compound extracted from a Chinese medicinal
plant Sinomenium acutum. It is a multitarget antitumor natural substance. Various …
plant Sinomenium acutum. It is a multitarget antitumor natural substance. Various …
Sinomenine inhibits non-small cell lung cancer via downregulation of hexokinases II-mediated aerobic glycolysis
Background Addiction to aerobic glycolysis is a common metabolic phenotype in human non-
small cell lung cancer (NSCLC). The natural product Sinomenine (Sin) exhibits significant …
small cell lung cancer (NSCLC). The natural product Sinomenine (Sin) exhibits significant …
[HTML][HTML] Sinomenine hydrochloride promotes TSHR-dependent redifferentiation in papillary thyroid cancer
J Zhang, A Zhao, X Jia, X Li, Y Liang, Y Liu… - International Journal of …, 2022 - mdpi.com
Radioactive iodine (RAI) plays an important role in the diagnosis and treatment of papillary
thyroid cancer (PTC). The curative effects of RAI therapy are not only related to …
thyroid cancer (PTC). The curative effects of RAI therapy are not only related to …
Preparation, synergism, and biocompatibility of in situ liquid crystals loaded with sinomenine and 5-Fluorouracil for treatment of liver cancer
J Cao, J Huang, S Gui, X Chu - International journal of …, 2021 - Taylor & Francis
Purpose Transarterial chemoembolization is the preferred treatment for patients with middle
and advanced-stage hepatocellular carcinoma (HCC); however, most hepatic artery …
and advanced-stage hepatocellular carcinoma (HCC); however, most hepatic artery …