Metalation and activation of Zn2+ enzymes via early secretory pathway-resident ZNT proteins

T Kambe, T Wagatsuma - Biophysics Reviews, 2023 - pubs.aip.org
Zinc (Zn 2+), an essential trace element, binds to various proteins, including enzymes,
transcription factors, channels, and signaling molecules and their receptors, to regulate their …

Taking a color photo: A homozygous 25-bp deletion in Bace2 may cause brown-and-white coat color in giant pandas

D Guan, S Sun, L Song, P Zhao, Y Nie, X Huang… - Proceedings of the …, 2024 - pnas.org
Brown-and-white giant pandas (hereafter brown pandas) are distinct coat color mutants
found exclusively in the Qinling Mountains, Shaanxi, China. However, its genetic …

An allelic series at the EDNRB2 locus controls diverse piebalding patterns in the domestic pigeon

ET Maclary, R Wauer, B Phillips, A Brown, EF Boer… - PLoS …, 2023 - journals.plos.org
Variation in pigment patterns within and among vertebrate species reflects underlying
changes in cell migration and function that can impact health, reproductive success, and …

A genome assembly of the American black bear, Ursus americanus, from California

MA Supple, M Escalona, J Adkins… - Journal of …, 2024 - academic.oup.com
Abstract The American black bear, Ursus americanus, is a widespread and ecologically
important species in North America. In California, the black bear plays an important role in a …

Gut Microbiome-Driven metabolites influence skin pigmentation in TYRP1 mutant Oujiang Color Common Carp

RN Mandal, J Ke, NH Kanika, X Hou, Z Zhang, P Zhang… - Gene, 2024 - Elsevier
The gut microbiome plays a key role in regulating the gut-skin axis, and host genetics
partially influence this regulation. The study investigated the role of gut microbiota and host …

[HTML][HTML] The Hoof Color of Australian White Sheep Is Associated with Genetic Variation of the MITF Gene

P Su, H Wu, Y Huang, X Lu, J Yin, Q Zhang, X Lan - Animals, 2023 - mdpi.com
Simple Summary In this research, we used RAD-seq genoty** data and GWAS to identify
SNPs in the MITF gene that were significantly associated with hoof color in the Australian …

Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp

RN Mandal, J Ke, NH Kanika, F Wang, J Wang… - BMC genomics, 2024 - Springer
Background Neither a TYRP1-mediated highly conserved genetic network underlying skin
color towards optimum defense nor the pathological tendency of its mutation is well …

Genetic variants in melanogenesis proteins TYRP1 and TYR are associated with the golden rhesus macaque phenotype

SM Peterson, MM Watowich, LM Renner… - G3: Genes …, 2023 - academic.oup.com
Nonhuman primates (NHPs) are vital translational research models due to their high
genetic, physiological, and anatomical homology with humans. The “golden” rhesus …

Identification of polymorphisms in TYRP1, DCT and RAB38 genes and their association with coat color in alpacas

C Melo-Rojas, PW Bravo-Matheus… - Frontiers in Animal …, 2023 - frontiersin.org
Objective The goal of this study was to characterize and investigate the effect of single
nucleotide polymorphisms (SNPs) or InDels in tyrosinase related protein 1 (TYRP1) …

Bear essentials

T Caro - Trends in Genetics, 2023 - cell.com
Strangely, American black bears come in many colours. New work by Puckett et al. shows
that a missense alteration in the gene encoding tyrosinase-related protein 1 (TYRP1) likely …