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Fibrosis: types, effects, markers, mechanisms for disease progression, and its relation with oxidative stress, immunity, and inflammation
Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …
Intricacies of TGF-β signaling in Treg and Th17 cell biology
Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …
central to the balance between immune tolerance and immune rejection. Th cells adopt …
Tumor microenvironment signaling and therapeutics in cancer progression
Tumor development and metastasis are facilitated by the complex interactions between
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
TGF-β signaling in the tumor metabolic microenvironment and targeted therapies
Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer
progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in …
progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in …
Targeting TGF-β signal transduction for fibrosis and cancer therapy
D Peng, M Fu, M Wang, Y Wei, X Wei - Molecular cancer, 2022 - Springer
Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …
in early embryonic development and organogenesis, immune supervision, tissue repair, and …
Subchondral bone microenvironment in osteoarthritis and pain
Osteoarthritis comprises several joint disorders characterized by articular cartilage
degeneration and persistent pain, causing disability and economic burden. The incidence of …
degeneration and persistent pain, causing disability and economic burden. The incidence of …
Transforming growth factor–β1 in regulatory T cell biology
Transforming growth factor–β1 (TGF-β1) is inextricably linked to regulatory T cell (Treg)
biology. However, precisely untangling the role for TGF-β1 in Treg differentiation and …
biology. However, precisely untangling the role for TGF-β1 in Treg differentiation and …
Exploring the trans‐cleavage activity of CRISPR‐Cas12a (cpf1) for the development of a universal electrochemical biosensor
An accurate, rapid, and cost‐effective biosensor for the quantification of disease biomarkers
is vital for the development of early‐diagnostic point‐of‐care systems. The recent discovery …
is vital for the development of early‐diagnostic point‐of‐care systems. The recent discovery …
Dynamic proteinaceous hydrogel enables in‐situ recruitment of endogenous TGF‐β1 and stem cells for cartilage regeneration
Q Guo, W Yin, H Wang, J Gao, Y Gu… - Advanced Functional …, 2024 - Wiley Online Library
Articular cartilage is a tissue with relatively poor self‐regeneration capacity due to
insufficient blood vessels and chondrocytes in the region. Biomaterial‐assisted tissue …
insufficient blood vessels and chondrocytes in the region. Biomaterial‐assisted tissue …
Green alternatives as antimicrobial agents in mitigating periodontal diseases: a narrative review
Periodontal diseases and dental caries are the most common infectious oral diseases
impacting oral health globally. Oral cavity health is crucial for enhancing life quality since it …
impacting oral health globally. Oral cavity health is crucial for enhancing life quality since it …