Metal ions play a key role in aggregation of amyloid β protein by interfering with their proper
folding, altering protein homeostasis and cell viability, and ultimately leading to …

Neurodegenerative disorders (NDDs) are a class of debilitating diseases that progressively
impair the protein structure and result in neurological dysfunction in the nervous system …

Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

Abstract Three novel complexes (1, 3 and 4) ligating N-substituted isatin thiosemicarbazone
derivatives have been synthesized and their structural and biological characteristics have …

Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …

Eight new organometallic Ru (II)–arene complexes of the type [RuCl2 (η6-arene)(η1-S-
aroylthiourea)](arene= p-cymene or benzene) were synthesized in order to evaluate the …

Abstract Ru (II)-benzene complexes (P1 and P2) were synthesized using a
thiosemicarbazone ligand (L1) in two different coordination modes, monodentate S and …

Misfolding and protein aggregation have been linked to numerous human
neurodegenerative disorders such as Alzheimer's, prion, and Parkinson's diseases …

A water-soluble binuclear organometallic Ru-p-cymene complex [Ru (η 6-p-cymene)(η 2-L)]
2 (1) was prepared from (E)-2-((1H-indol-3-yl) methylene)-N-phenylhydrazine-1 …

Aims Alzheimer's disease (AD) is the most common type of dementia in which oxidative
stress plays an important role. In this disease, learning and memory and the cellular …