PET versus SPECT: strengths, limitations and challenges

A Rahmim, H Zaidi - Nuclear medicine communications, 2008 - journals.lww.com
The recent introduction of high-resolution molecular imaging technology is considered by
many experts as a major breakthrough that will potentially lead to a revolutionary paradigm …

Application of silicon photomultipliers to positron emission tomography

E Roncali, SR Cherry - Annals of biomedical engineering, 2011 - Springer
Historically, positron emission tomography (PET) systems have been based on scintillation
crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency …

Transparent adult zebrafish as a tool for in vivo transplantation analysis

RM White, A Sessa, C Burke, T Bowman, J LeBlanc… - Cell stem cell, 2008 - cell.com
The zebrafish is a useful model for understanding normal and cancer stem cells, but
analysis has been limited to embryogenesis due to the opacity of the adult fish. To address …

Simultaneous PET-MRI: a new approach for functional and morphological imaging

MS Judenhofer, HF Wehrl, DF Newport, C Catana… - Nature medicine, 2008 - nature.com
Noninvasive imaging at the molecular level is an emerging field in biomedical research. This
paper introduces a new technology synergizing two leading imaging methodologies …

Long-term propagation of distinct hematopoietic differentiation programs in vivo

B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton… - Cell stem cell, 2007 - cell.com
Heterogeneity in the differentiation behavior of hematopoietic stem cells is well documented
but poorly understood. To investigate this question at a clonal level, we isolated a …

PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)–conjugated radiolabeled iron oxide nanoparticles

HY Lee, Z Li, K Chen, AR Hsu, C Xu, J **e… - Journal of Nuclear …, 2008 - Soc Nuclear Med
The purpose of this study was to develop a bifunctional iron oxide (IO) nanoparticle probe for
PET and MRI scans of tumor integrin αvβ3 expression. Methods: Polyaspartic acid (PASP) …

Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI

BJ Pichler, MS Judenhofer, C Catana… - Journal of Nuclear …, 2006 - Soc Nuclear Med
PET combined with CT has proven to be a valuable multimodality imaging device revealing
both functional and anatomic information. Although PET/CT has become completely …

NEMA NU 4-2008 comparison of preclinical PET imaging systems

AL Goertzen, Q Bao, M Bergeron… - Journal of nuclear …, 2012 - Soc Nuclear Med
The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for
performance measurements of small-animal tomographs was recently published. Before this …

Performance evaluation of the inveon dedicated PET preclinical tomograph based on the NEMA NU-4 standards

Q Bao, D Newport, M Chen, DB Stout… - Journal of Nuclear …, 2009 - Soc Nuclear Med
The Inveon dedicated PET (DPET) scanner is the latest generation of preclinical PET
systems devoted to high-resolution and high-sensitivity murine model imaging. In this study …

Performance evaluation of the GE healthcare eXplore VISTA dual-ring small-animal PET scanner

Y Wang, J Seidel, BMW Tsui, JJ Vaquero… - Journal of Nuclear …, 2006 - Soc Nuclear Med
We evaluated the performance characteristics of the eXplore VISTA dual-ring small-animal
PET scanner, a stationary, ring-type, depth-of-interaction (DOI) correcting system designed …