Abstract Context The European Association of Urology (EAU) guidelines panel on upper
urinary tract urothelial carcinoma (UTUC) has updated the guidelines to aid clinicians in …

Non-muscle-invasive bladder cancer (NMIBC) is an early-stage cancer without invasion into
the detrusor muscle layer. Transurethral resection of bladder tumour (TURBT) is a diagnostic …

Purpose: The purpose of this guideline is to provide a useful reference on the effective
evidence-based diagnoses and management of non-metastatic upper tract urothelial …

Background FGFR3-altered urothelial cancer (UC) correlates with a non-T cell-inflamed
phenotype and has therefore been postulated to be less responsive to immune checkpoint …

Upper urinary tract urothelial carcinoma (UTUC) is one of the common urothelial cancers. Its
molecular pathogenesis, however, is poorly understood, with no useful biomarkers available …

The combination of targeted therapy with immune checkpoint inhibition (ICI) is an area of
intense interest. We studied the interaction of fibroblast growth factor receptor (FGFR) …

Several fibroblast growth factor receptor (FGFR) inhibitors are approved or in clinical
development for the treatment of FGFR-driven urothelial cancer, and molecular mechanisms …

Abstract Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment
failure, suggesting that patients could benefit from a more personalized treatment approach …

Upper tract urothelial carcinoma (UTUC) is characterized by a distinctly aggressive clinical
phenotype. To define the biological features driving this phenotype, we performed an …

Purpose HER2 alterations are potential candidates for targeted treatments in metastatic
urothelial/bladder cancer (mUC). ERBB2 gene amplification and mutations are found in …