Increased glucose metabolism and uptake are characteristic of many tumors and used
clinically to diagnose and monitor cancer progression. In addition to cancer cells, the tumor …

Oncogenic signalling and metabolic alterations are interrelated in cancer cells. mTOR,
which is frequently activated in cancer, controls cell growth and metabolism. mTOR …

Simple Summary In this review, we describe arginine's role as a signaling metabolite,
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Biomimetic nanotechnology through camouflaging synthetic nanoparticles (NPs) with
natural cell membranes, which bestows with immune evasion and superior targeting …

Autophagy captures intracellular components and delivers them to lysosomes, where they
are degraded and recycled to sustain metabolism and to enable survival during starvation …

Macroautophagy (referred to here as autophagy) degrades and recycles cytoplasmic
constituents to sustain cellular and mammalian metabolism and survival during starvation …

It has been appreciated for nearly 100 years that cancer cells are metabolically distinct from
resting tissues. More recently understood is that this metabolic phenotype is not unique to …

Solid tumors reside in harsh tumor microenvironments (TMEs) together with various stromal
cell types. During tumor progression and metastasis, both tumor and stromal cells undergo …

Nanomedicine research has advanced dramatically in recent decades. Nonetheless,
traditional nanomedicine faces significant obstacles such as the low concentration of the …