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Chronic wounds
V Falanga, RR Isseroff, AM Soulika… - Nature Reviews …, 2022 - nature.com
Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …
and have emerged as an increasingly important clinical problem over the past several …
The functions and unique features of long intergenic non-coding RNA
Long intergenic non-coding RNA (lincRNA) genes have diverse features that distinguish
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …
Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers
Y Li, T Jiang, W Zhou, J Li, X Li, Q Wang, X **… - Nature …, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression
and they play fundamental roles in immune regulation. Here we introduce an integrated …
and they play fundamental roles in immune regulation. Here we introduce an integrated …
[HTML][HTML] The translational landscape of the human heart
Gene expression in human tissue has primarily been studied on the transcriptional level,
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …
largely neglecting translational regulation. Here, we analyze the translatomes of 80 human …
Mechanisms of long noncoding RNA function in development and disease
SU Schmitz, P Grote, BG Herrmann - Cellular and molecular life sciences, 2016 - Springer
Since decades it has been known that non-protein-coding RNAs have important cellular
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …
Long noncoding RNA in cancer: wiring signaling circuitry
C Lin, L Yang - Trends in cell biology, 2018 - cell.com
Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the
human genome, may hold missing drivers of cancer and have gained attention recently as a …
human genome, may hold missing drivers of cancer and have gained attention recently as a …
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
KA Lennox, MA Behlke - Nucleic acids research, 2016 - academic.oup.com
Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells.
Some have important functions and their dysregulation can contribute to a variety of disease …
Some have important functions and their dysregulation can contribute to a variety of disease …
[HTML][HTML] The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
The histone-modifying complexes PRC2 and TrxG/MLL play pivotal roles in determining the
activation state of genes controlling pluripotency, lineage commitment, and cell …
activation state of genes controlling pluripotency, lineage commitment, and cell …
Lung development: orchestrating the generation and regeneration of a complex organ
M Herriges, EE Morrisey - Development, 2014 - journals.biologists.com
The respiratory system, which consists of the lungs, trachea and associated vasculature, is
essential for terrestrial life. In recent years, extensive progress has been made in defining …
essential for terrestrial life. In recent years, extensive progress has been made in defining …