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Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques
LA Clifton, RA Campbell, F Sebastiani… - Advances in Colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …
membranes or biomembranes are used as platforms to understand fundamental properties …
[HTML][HTML] Neutron reflectometry as a powerful tool to elucidate membrane interactions of drug delivery systems
L Caselli, T Nylander, M Malmsten - Advances in Colloid and Interface …, 2024 - Elsevier
The last couple of decades have seen an explosion of novel colloidal drug delivery systems,
which have been demonstrated to increase drug efficacy, reduce side-effects, and provide …
which have been demonstrated to increase drug efficacy, reduce side-effects, and provide …
Membrane interactions of virus-like mesoporous silica nanoparticles
SM Haffner, E Parra-Ortiz, KL Browning, E Jørgensen… - ACS …, 2021 - ACS Publications
In the present study, we investigated lipid membrane interactions of silica nanoparticles as
carriers for the antimicrobial peptide LL-37 (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNL…) …
carriers for the antimicrobial peptide LL-37 (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNL…) …
Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein
S Busatto, Y Yang, SA Walker, I Davidovich… - Journal of …, 2020 - Springer
Background Cancer cell-derived extracellular vesicles (EVs) have previously been shown to
contribute to pre-metastatic niche formation. Specifically, aggressive tumors secrete pro …
contribute to pre-metastatic niche formation. Specifically, aggressive tumors secrete pro …
Escherichia coli “TatExpress” strains super‐secrete human growth hormone into the bacterial periplasm by the Tat pathway
DF Browning, KL Richards, AR Peswani… - Biotechnology and …, 2017 - Wiley Online Library
Numerous high‐value proteins are secreted into the Escherichia coli periplasm by the
General Secretory (Sec) pathway, but Sec‐based production chassis cannot handle many …
General Secretory (Sec) pathway, but Sec‐based production chassis cannot handle many …
Peptide-Loaded Cubosomes Functioning as an Antimicrobial Unit against Escherichia coli
L Boge, KL Browning, R Nordstrom… - … Applied Materials & …, 2019 - ACS Publications
Dispersions of cubic liquid crystalline phases, also known as cubosomes, have shown great
promise as delivery vehicles for a wide range of medicines. Due to their ordered structure …
promise as delivery vehicles for a wide range of medicines. Due to their ordered structure …
[HTML][HTML] SARS-CoV-2 spike protein removes lipids from model membranes and interferes with the capacity of high density lipoprotein to exchange lipids
Y Correa, S Waldie, M Thépaut, S Micciulla… - Journal of Colloid and …, 2021 - Elsevier
Cholesterol has been shown to affect the extent of coronavirus binding and fusion to cellular
membranes. The severity of Covid-19 infection is also known to be correlated with lipid …
membranes. The severity of Covid-19 infection is also known to be correlated with lipid …
[HTML][HTML] Screening of the binding affinity of serum proteins to lipid nanoparticles in a cell free environment
F Sebastiani, MY Arteta, L Lindfors… - Journal of Colloid and …, 2022 - Elsevier
Lipid nanoparticles (LNPs) are promising drug and gene carriers. Upon intravenous
administration, LNPs' experience different degree of cellular uptake depending on their …
administration, LNPs' experience different degree of cellular uptake depending on their …
Interactions among dietary phytochemicals and nutrients: Role of cell membranes
Background The health effects of dietary phytochemicals (eg., carotenoids, flavonoids,
phenolic acids) and their interactions with each other or nutrients (eg., carbohydrate …
phenolic acids) and their interactions with each other or nutrients (eg., carbohydrate …
Cholesterol transfer at the plasma membrane
M Axmann, WM Strobl, B Plochberger, H Stangl - Atherosclerosis, 2019 - Elsevier
Cholesterol homeostasis is of central importance for life. Therefore, cells have developed a
divergent set of pathways to meet their cholesterol needs. In this review, we focus on the …
divergent set of pathways to meet their cholesterol needs. In this review, we focus on the …