Perturbing the muscle work loop paradigm to unravel the neuromechanics of unsteady locomotion

S Sponberg, E Abbott… - Journal of Experimental …, 2023 - journals.biologists.com
Muscle function during movement is more than a simple, linear transformation of neural
activity into force. The classic work loop technique has pioneered our understanding of …

[HTML][HTML] Reduced Achilles tendon stiffness disrupts calf muscle neuromechanics in elderly gait

RL Krupenevich, ON Beck, GS Sawicki, JR Franz - Gerontology, 2022 - karger.com
Older adults walk slower and with a higher metabolic energy expenditure than younger
adults. In this review, we explore the hypothesis that age-related declines in Achilles tendon …

A simple model to estimate plantarflexor muscle–tendon mechanics and energetics during walking with elastic ankle exoskeletons

GS Sawicki, NS Khan - IEEE Transactions on Biomedical …, 2015 - ieeexplore.ieee.org
Goal: A recent experiment demonstrated that when humans wear unpowered elastic ankle
exoskeletons with intermediate spring stiffness, they can reduce their metabolic energy cost …

Integrating muscle energetics into biomechanical models to understand variance in the cost of movement

GA Lichtwark, LN Jessup, RN Konno… - Journal of …, 2025 - journals.biologists.com
In this Review, we explore the state of the art of biomechanical models for estimating energy
consumption during terrestrial locomotion. We consider different mechanical models that …

Timing matters: tuning the mechanics of a muscle–tendon unit by adjusting stimulation phase during cyclic contractions

GS Sawicki, BD Robertson, E Azizi… - Journal of …, 2015 - journals.biologists.com
ABSTRACT A growing body of research on the mechanics and energetics of terrestrial
locomotion has demonstrated that elastic elements acting in series with contracting muscle …

Predictive control of musculotendon loads across fast and slow-twitch muscles in a simulated system with parallel actuation

M Nabipour, GS Sawicki, M Sartori - Wearable Technologies, 2025 - cambridge.org
Research in lower limb wearable robotic control has largely focused on reducing the
metabolic cost of walking or compensating for a portion of the biological joint torque, for …

Unconstrained muscle-tendon workloops indicate resonance tuning as a mechanism for elastic limb behavior during terrestrial locomotion

BD Robertson, GS Sawicki - Proceedings of the National Academy of …, 2015 - pnas.org
In terrestrial locomotion, there is a missing link between observed spring-like limb
mechanics and the physiological systems driving their emergence. Previous modeling and …

Slack-based tunable dam** leads to a trade-off between robustness and efficiency in legged locomotion

A Mo, F Izzi, EC Gönen, D Haeufle… - Scientific Reports, 2023 - nature.com
Animals run robustly in diverse terrain. This locomotion robustness is puzzling because
axon conduction velocity is limited to a few tens of meters per second. If reflex loops deliver …

Humans falling in holes: adaptations in lower-limb joint mechanics in response to a rapid change in substrate height during human hop**

TJM Dick, LK Punith… - Journal of the Royal …, 2019 - royalsocietypublishing.org
In getting from here to there, we continuously negotiate complex environments and
unpredictable terrain. Our ability to stay upright in the face of obstacles, such as holes in the …

Sensor-Motor Maps for Describing Linear Reflex Composition in Hop**

C Schumacher, A Seyfarth - Frontiers in computational neuroscience, 2017 - frontiersin.org
In human and animal motor control several sensory organs contribute to a network of
sensory pathways modulating the motion depending on the task and the phase of execution …