[HTML][HTML] The role of gut microbiota, exosomes, and their interaction in the pathogenesis of ALD

Z Cheng, L Yang, H Chu - Journal of Advanced Research, 2024 - Elsevier
Background The liver disorders caused by alcohol abuse are termed alcoholic-related liver
disease (ALD), including alcoholic steatosis, alcoholic steatohepatitis alcoholic hepatitis …

Exosomes as new biomarkers and drug delivery tools for the prevention and treatment of various diseases: current perspectives

Q Liu, S Li, A Dupuy, H Mai, N Sailliet, C Logé… - International Journal of …, 2021 - mdpi.com
Exosomes are nano-sized vesicles secreted by most cells that contain a variety of biological
molecules, such as lipids, proteins and nucleic acids. They have been recognized as …

Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12

Y Teng, F Xu, X Zhang, J Mu, M Sayed, X Hu, C Lei… - Molecular Therapy, 2021 - cell.com
Lung inflammation is a hallmark of coronavirus disease 2019 (COVID-19). In this study, we
show that mice develop inflamed lung tissue after being administered exosomes released …

Fabrication of poly (sarcosine), poly (ethylene glycol), and poly (lactic-co-glycolic acid) polymeric nanoparticles for cancer drug delivery

S Bhattacharya - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
The most significant advantage of polymeric nanoparticles is their systematic and target
specific drug delivery properties. These polymeric nanoparticles have the potential to …

Robust and persistent SARS-CoV-2 infection in the human intestinal brush border expressing cells

S Lee, GY Yoon, J Myoung, SJ Kim… - Emerging Microbes & …, 2020 - Taylor & Francis
Studies on patients with the coronavirus disease-2019 (COVID-19) have implicated that the
gastrointestinal (GI) tract is a major site of severe acute respiratory syndrome coronavirus 2 …

Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication

Z Ruan, Y Liang, Z Chen, J Yin, C Li, P Pan… - Frontiers in …, 2022 - frontiersin.org
Human enterovirus 71 (EV71) is one of the major agents of the hand, foot, and mouth
disease (HFMD), and occasionally causes severe neurological complications. There is …

Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells

J Mamana, GM Humber, ER Espinal, S Seo… - Frontiers in Cellular …, 2023 - frontiersin.org
Coxsackievirus B3 (CVB3) is a significant human pathogen that is commonly found
worldwide. CVB3 among other enteroviruses, are the leading causes of aseptic meningo …

Recent advances in the understanding of enterovirus A71 infection: a focus on neuropathogenesis

HK Tee, MI Zainol, IC Sam, YF Chan - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Hand, foot, and mouth disease caused by enterovirus A71 (EV-A71) is more
frequently associated with neurological complications and deaths compared to other …

TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular …

S Sawaged, T Mota, H Piplani, R Thakur, D Lall… - PLoS …, 2022 - journals.plos.org
Host-pathogen dynamics are constantly at play during enteroviral infection. Coxsackievirus
B (CVB) is a common juvenile enterovirus that infects multiple organs and drives …

A perspective on organoids for virology research

A Sridhar, S Simmini, CMS Ribeiro, C Tapparel… - Viruses, 2020 - mdpi.com
Animal models and cell lines are invaluable for virology research and host–pathogen
interaction studies. However, it is increasingly evident that these models are not sufficient to …