The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …

Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify
appropriate antiretroviral regimes, and characterize transmission dynamics. Despite …

Next generation sequencing (NGS) is a trending new standard for genotypic HIV-1 drug
resistance (HIVDR) testing. Many NGS HIVDR data analysis pipelines have been …

The use of NGS technologies on HIV DR testing will allow unprecedented insights into
genomic structures of virus populations that may be of immediate relevance to both clinical …

Next-generation sequencing (NGS) is increasingly used for HIV-1 drug resistance
genoty**. NGS methods have the potential for a more sensitive detection of low …

Detection of HIV drug resistance (HIVDR) is vital to successful anti‐retroviral therapy (ART).
HIVDR testing to determine drug‐resistance mutations is routinely performed in Australia to …

Background The presence of high-abundance drug-resistant HIV-1 jeopardizes success of
antiretroviral therapy (ART). Despite numerous investigations, the clinical impact of low …

Conventional HIV drug resistance (HIVDR) genoty** utilizes Sanger sequencing (SS)
methods, which are limited by low data throughput and the inability of detecting low …

Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …