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Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos
A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …
Liquid antisolvent crystallization of pharmaceutical compounds: current status and future perspectives
The present work reviews the liquid antisolvent crystallization (LASC) to prepare the
nanoparticle of pharmaceutical compounds to enhance their solubility, dissolution rate, and …
nanoparticle of pharmaceutical compounds to enhance their solubility, dissolution rate, and …
Effects of different physicochemical characteristics and supersaturation principle of solidified SNEDDS and surface-modified microspheres on the bioavailability of …
JE Choi, JS Kim, MJ Choi, K Baek, MR Woo… - International Journal of …, 2021 - Elsevier
In this study, a solidified self-nanoemulsifying drug delivery system (solidified SNEDDS) and
surface-modified microspheres were developed for enhancing the oral bioavailability of …
surface-modified microspheres were developed for enhancing the oral bioavailability of …
[HTML][HTML] Investigation of patient-centric 3D-printed orodispersible films containing amorphous aripiprazole
The objective of this study was to design and evaluate an orodispersible film (ODF)
composed of aripiprazole (ARP), prepared using a conventional solvent casting technique …
composed of aripiprazole (ARP), prepared using a conventional solvent casting technique …
A Lipophilic Salt Form to Enhance the Lipid Solubility and Certain Biopharmaceutical Properties of Lapatinib
Lapatinib (LTP) commercially available as lapatinib ditosylate (LTP-DTS) salt is the only
drug approved for the treatment of HER-positive metastatic breast cancer. A low and pH …
drug approved for the treatment of HER-positive metastatic breast cancer. A low and pH …
Pharmaceutical methods for enhancing the dissolution of poorly water-soluble drugs
T Mahmood, RM Sarfraz, A Ismail, M Ali… - ASSAY and Drug …, 2023 - liebertpub.com
Low water solubility is the main hindrance in the growth of pharmaceutical industry.
Approximately 90% of newer molecules under investigation for drugs and 40% of novel …
Approximately 90% of newer molecules under investigation for drugs and 40% of novel …
Nanogels Based on N, N-Dimethylacrylamide and β-Cyclodextrin Triacrylate for Enhanced Solubility and Therapeutic Efficacy of Aripiprazole
S Stoilova, D Georgieva, R Mihaylova, PD Petrov… - Gels, 2024 - mdpi.com
Aripiprazole (ARZ) is a medication used for the treatment of various diseases such as
schizophrenia, bipolar disorder, major depressive disorder, autism, and Tourette's …
schizophrenia, bipolar disorder, major depressive disorder, autism, and Tourette's …
Self-emulsifying Drug Delivery Systems: Concept to Applications, Regulatory Issues, Recent Patents, Current Challenges and Future Directions
RL Maharana, S Swain, SK Mahapatra… - Current …, 2025 - benthamdirect.com
Self-emulsifying drug delivery systems (SEDDS) can increase the solubility and
bioavailability of poorly soluble drugs. The inability of 35% to 40% of new pharmaceuticals …
bioavailability of poorly soluble drugs. The inability of 35% to 40% of new pharmaceuticals …
Development and optimization of nanoparticles loaded with erucin, a dietary isothiocyanate isolated from Eruca sativa: Antioxidant and antiproliferative activities in …
The study on Erucin (ER) has gained interest of nutraceutical and pharmaceutical industries
because of its anti-cancer properties. Erucin is an isothiocyanate obtained from the seeds of …
because of its anti-cancer properties. Erucin is an isothiocyanate obtained from the seeds of …
Applications of innovative technologies to the delivery of antipsychotics
Psychosis is a high-incidence pathology associated with a profound alteration in the
perception of reality. The limitations of drugs available on the market have stimulated the …
perception of reality. The limitations of drugs available on the market have stimulated the …