Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …

Metabolism is an integrated network of biochemical pathways that assemble to generate the
robust, responsive physiologies of microorganisms. Despite decades of fundamental studies …

The fungus Candida glabrata and the bacterium Staphylococcus epidermidis are important
biofilm-forming microorganisms responsible of nosocomial infections in patients. In addition …

Acinetobacter baumannii has become a leading cause of bacterial nosocomial infections, in
part, due to its ability to resist desiccation, disinfection and antibiotics. Several factors …

In Salmonella enterica, the absence of the RidA deaminase results in the accumulation of
the reactive enamine 2-aminoacrylate (2AA). The resulting 2AA stress impacts metabolism …

Metabolites are prone to damage, either via enzymatic side reactions, which collectively
form the underground metabolism, or via spontaneous chemical reactions. The resulting non …

Microbes are natural chemical factories and their metabolome comprise diverse arrays of
chemicals. The genus Xanthomonas comprises some of the most important plant pathogens …

Reactive intermediate deaminase A (RidA) is a highly conserved enzyme that catalyzes the
hydrolysis of 2‐imino acids to the corresponding 2‐keto acids and ammonia. RidA thus …

Defining the physiological role of a gene product relies on interpreting phenotypes caused
by the lack, or alteration, of the respective gene product. Mutations in critical genes often …

Abstract Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families
among which the RidA is conserved in all domains of life. RidA proteins accelerate the …