[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy
C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …
[HTML][HTML] Reconfiguration of DNA methylation in aging
M Zampieri, F Ciccarone, R Calabrese… - Mechanisms of ageing …, 2015 - Elsevier
A complex interplay between multiple biological effects shapes the aging process. The
advent of genome-wide quantitative approaches in the epigenetic field has highlighted the …
advent of genome-wide quantitative approaches in the epigenetic field has highlighted the …
Epigenetics and aging: the targets and the marks
MF Fraga, M Esteller - Trends in genetics, 2007 - cell.com
'Aging epigenetics' is an emerging field that promises exciting revelations in the near future.
Here we focus on the functional and biological significance of the epigenetic alterations that …
Here we focus on the functional and biological significance of the epigenetic alterations that …
Oxidative stress and epigenetic regulation in ageing and age-related diseases
Recent statistics indicate that the human population is ageing rapidly. Healthy, but also
diseased, elderly people are increasing. This trend is particularly evident in Western …
diseased, elderly people are increasing. This trend is particularly evident in Western …
Epigenetic alterations in aging
S Gonzalo - Journal of applied physiology, 2010 - journals.physiology.org
Aging is a multifaceted process characterized by genetic and epigenetic changes in the
genome. The genetic component of aging received initially all of the attention. Telomere …
genome. The genetic component of aging received initially all of the attention. Telomere …
Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein
Background & Aims: The involvement of the hepatitis B virus X (HBx) protein in epigenetic
modifications during hepatocarcinogenesis has not been previously characterized. The aim …
modifications during hepatocarcinogenesis has not been previously characterized. The aim …
From healthy aging to frailty: in search of the underlying mechanisms
P Brivio, MS Paladini, G Racagni… - Current medicinal …, 2019 - ingentaconnect.com
Population aging is accelerating rapidly worldwide, from 461 million people older than 65
years in 2004 to an estimated 2 billion people by 2050, leading to critical implications for the …
years in 2004 to an estimated 2 billion people by 2050, leading to critical implications for the …
DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging
Experimental studies demonstrated that maternal exposure to certain environmental and
dietary factors during early embryonic development can influence the phenotype of offspring …
dietary factors during early embryonic development can influence the phenotype of offspring …
Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis
Both AP-1 and PRMT1 are vital molecules in variety of cellular progresssion, but the
interaction between these proteins in the context of cellular functions is less clear. Gastric …
interaction between these proteins in the context of cellular functions is less clear. Gastric …
A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
The central importance of epigenetics to the aging process is increasingly being recognized.
Here we perform a methylome-wide association study (MWAS) of aging in whole blood DNA …
Here we perform a methylome-wide association study (MWAS) of aging in whole blood DNA …