Tuberculosis (TB) is a contagious infectious disease caused by the TB‐causing bacillus
Mycobacterium tuberculosis and is considered a public health problem with enormous …

Diabetes is an endocrinological disorder with a rapidly increasing number of patients
globally. Over the last few years, the alarming status of diabetes has become a pivotal factor …

Mycobacterium avium subsp. paratuberculosis is a zoonotic pathogen whose association
with Crohn's disease in humans is under scrutiny. The objective of this work was to …

Type 1 diabetes mellitus (T1DM) is a multifactorial autoimmune disease in which the insulin
producing β cell population is destroyed by the infiltrated T lymphocytes. Even though the …

Background Helminthiasis and tuberculosis (TB) coincide geographically and there is much
interest in exploring how concurrent worm infections might alter immune responses against …

DNA-hsp65, a DNA vaccine encoding the 65-kDa heat-shock protein of Mycobacterium
leprae (Hsp65) is capable of inducing the reduction of established tumors in mouse models …

Heat-shock proteins are molecules with extensive data showing their potential as
immunomodulators of different types of diseases. The gene of HSP65 from Mycobacterium …

Mycobacterium tuberculosis was one of the first human pathogens to be identified as the
cause of a specific disease–TB. TB was also one of the first specific diseases for which …

Summary CD 4+ F oxp3+ regulatory T cells inhibit the production of interferon‐γ, which is the
major mediator of protection against M ycobacterium tuberculosis infection. In this study, we …

Background Our group previously demonstrated that a DNA plasmid encoding the
mycobacterial 65-kDa heat shock protein (DNA-HSP65) displayed prophylactic and …