Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Insights into human history from the first decade of ancient human genomics

Y Liu, X Mao, J Krause, Q Fu - Science, 2021 - science.org
Recent advancements in DNA sequencing technologies and laboratory preparation
protocols have rapidly expanded the scope of ancient DNA research over the past decade …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Accurate detection of identity-by-descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick, I Olalde… - Nature …, 2024 - nature.com
Long DNA segments shared between two individuals, known as identity-by-descent (IBD),
reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying …

The genetic history of the Southern Arc: A bridge between West Asia and Europe

I Lazaridis, S Alpaslan-Roodenberg, A Acar, A Açıkkol… - Science, 2022 - science.org
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …

Large-scale migration into Britain during the Middle to Late Bronze Age

N Patterson, M Isakov, T Booth, L Büster, CE Fischer… - Nature, 2022 - nature.com
Present-day people from England and Wales have more ancestry derived from early
European farmers (EEF) than did people of the Early Bronze Age. To understand this, here …

Dairying, diseases and the evolution of lactase persistence in Europe

RP Evershed, G Davey Smith, M Roffet-Salque… - Nature, 2022 - nature.com
Abstract In European and many African, Middle Eastern and southern Asian populations,
lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over …

The Anglo-Saxon migration and the formation of the early English gene pool

J Gretzinger, D Sayer, P Justeau, E Altena, M Pala… - Nature, 2022 - nature.com
The history of the British Isles and Ireland is characterized by multiple periods of major
cultural change, including the influential transformation after the end of Roman rule, which …

Getting genetic ancestry right for science and society

ACF Lewis, SJ Molina, PS Appelbaum, B Dauda… - Science, 2022 - science.org
Glaring health disparities have reinvigorated debate about the relevance of race to health,
including how race should and should not be used as a variable in research and …

Language trees with sampled ancestors support a hybrid model for the origin of Indo-European languages

P Heggarty, C Anderson, M Scarborough, B King… - Science, 2023 - science.org
The origins of the Indo-European language family are hotly disputed. Bayesian phylogenetic
analyses of core vocabulary have produced conflicting results, with some supporting a …