Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Camptothecin-based prodrug nanomedicines for cancer therapy

R Zhang, J Yu, Z Guo, H Jiang, C Wang - Nanoscale, 2023 - pubs.rsc.org
Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication of cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide-spectrum antitumour …

Stimulus‐Responsive Nano‐Prodrug Strategies for Cancer Therapy: A Focus on Camptothecin Delivery

B Chu, H Deng, T Niu, Y Qu, Z Qian - Small methods, 2024 - Wiley Online Library
Camptothecin (CPT) is a highly cytotoxic molecule with excellent antitumor activity against
various cancers. However, its clinical application is severely limited by poor water solubility …

Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Advanced Application of Polymer Nanocarriers in Delivery of Active Ingredients from Traditional Chinese Medicines

Z Zhai, J Niu, L Xu, J Xu - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
Active ingredients from Traditional Chinese Medicines (TCMs) have been a cornerstone of
healthcare for millennia, offering a rich source of bioactive compounds with therapeutic …

Enhancing camptothecin loading and release control through physical surface modification of organosilica nanoparticles with polyethylene glycol

HVT Nguyen, VH Tran, LB Vong, TTN Tran… - Colloids and Surfaces A …, 2024 - Elsevier
The surface modification of nanoparticles holds the potential to enhance the loading
capacity of drug molecules and regulate their release, making it possible to exploit the …

pH-responsive materials based on sodium carboxymethyl cellulose as a safe and effective strategy for camptothecin delivery

C Su, G Liu, M Wang, H Gao, Y Zou, J Gao - Colloids and Surfaces A …, 2023 - Elsevier
The safe and efficient delivery of drugs is regarded as a fundamental strategy for enhancing
the low effectiveness of cancer treatments. Herein, a simple preparation approach for a …

Reactive oxygen species-responsive nano-platform with dual-targeting and fluorescent lipid-specific imaging capabilities for the management of atherosclerotic …

Z He, Q Chen, X Duan, Y Zhong, L Zhu, N Mou, X Yang… - Acta Biomaterialia, 2024 - Elsevier
Atherosclerosis (AS), a pathological cause of cardiovascular disease, results from
endothelial injury, local progressive inflammation, and excessive lipid accumulation. AS …

Co-Administration of Chemo-Phototherapeutic Loaded Lignin Nanoarchitecture for the Treatment of Skin Cancer Cell Lines and Bacterial Infections

S Paul, A De, S Kirar, NS Thakur… - ACS Applied Nano …, 2024 - ACS Publications
Epidermoid carcinoma is the utmost frequent type of skin cancer worldwide resulting in
bacterial infection-induced chronic wounds. The primary available treatment option is …

Polymeric Nanomaterials in 3D Bioprinting for Tissue Engineering and Drug Delivery Applications

S Han, JP Fisher, AG Mikos, KJ Hogan - Bioprinting, 2024 - Elsevier
Nanoparticles have been broadly investigated in 3D bioprinting (3DBP) for various
purposes, including drug delivery, enhanced mechanical performance, biocompatibility, and …