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The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …
physiological and pathological events in biology. Metal coordination chemistry, especially …
Oxidative stress and neurodegeneration: where are we now?
The brain and nervous system are prone to oxidative stress, and are inadequately equipped
with antioxidant defense systems to prevent 'ongoing'oxidative damage, let alone the extra …
with antioxidant defense systems to prevent 'ongoing'oxidative damage, let alone the extra …
How biology handles nitrite
Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
When bad things happen to good fish: the loss of hemoglobin and myoglobin expression in Antarctic icefishes
SUMMARY The Antarctic icefishes (Family Channichthyidae) provide excellent examples of
unique traits that can arise in a chronically cold and isolated environment. Their loss of …
unique traits that can arise in a chronically cold and isolated environment. Their loss of …
Neuroglobin and cytoglobin in search of their role in the vertebrate globin family
Neuroglobin and cytoglobin are two recent additions to the family of heme-containing
respiratory proteins of man and other vertebrates. Here, we review the present state of …
respiratory proteins of man and other vertebrates. Here, we review the present state of …
What is the function of neuroglobin?
For a long time, haemoglobin and myoglobin had been assumed to represent the only
globin types of vertebrates. In 2000, however, we discovered a third globin type by mining …
globin types of vertebrates. In 2000, however, we discovered a third globin type by mining …
Neuroglobin, nitric oxide, and oxygen: functional pathways and conformational changes
Neuroglobin (Ngb) is a globin expressed in the nervous system of humans and other
organisms that is involved in the protection of the brain from ischemic damage. Despite …
organisms that is involved in the protection of the brain from ischemic damage. Despite …
Neuroglobin: From structure to function in health and disease
In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
Comparative Effects of Direct Cadmium Contamination on Gene Expression in Gills, Liver, Skeletal Muscles and Brain of the Zebrafish (Danio rerio)
The effects of cadmium (Cd) on gene expression were examined in four organs (gills, liver,
skeletal muscles and brain) of the zebrafish. Adult male fish were subjected to three different …
skeletal muscles and brain) of the zebrafish. Adult male fish were subjected to three different …
Structure and reactivity of hexacoordinate hemoglobins
The heme prosthetic group in hemoglobins is most often attached to the globin through
coordination of either one or two histidine side chains. Those proteins with one histidine …
coordination of either one or two histidine side chains. Those proteins with one histidine …