Walking on common ground: a cross-disciplinary sco** review on the clinical utility of digital mobility outcomes

A Polhemus, L Delgado-Ortiz, G Brittain… - NPJ digital …, 2021‏ - nature.com
Physical mobility is essential to health, and patients often rate it as a high-priority clinical
outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count …

Health-related quality of life in patients with multiple sclerosis: impact of disease-modifying drugs

PJ Jongen - CNS drugs, 2017‏ - Springer
Multiple sclerosis (MS) has a profound impact on health-related quality of life (HRQoL), a
comprehensive subjective measure of the patient's health status. Assessment of HRQoL …

Optimizing exoskeleton assistance for faster self-selected walking

S Song, SH Collins - IEEE Transactions on Neural Systems and …, 2021‏ - ieeexplore.ieee.org
Self-selected walking speed is an important aspect of mobility. Exoskeletons can increase
walking speed, but the mechanisms behind these changes and the upper limits on …

Multimodal sensing and intuitive steering assistance improve navigation and mobility for people with impaired vision

P Slade, A Tambe, MJ Kochenderfer - Science robotics, 2021‏ - science.org
Globally, more than 250 million people have impaired vision and face challenges navigating
outside their homes, affecting their independence, mental health, and physical health …

Efficacy of high‐intensity aerobic exercise on common multiple sclerosis symptoms

M Langeskov‐Christensen, LG Hvid… - Acta Neurologica …, 2022‏ - Wiley Online Library
Objectives Fatigue and walking impairment are disabling symptoms of multiple sclerosis
(MS). We investigated the effects of progressive aerobic exercise (PAE) on fatigue, walking …

Effects of walking interventions in persons with multiple sclerosis–A systematic review

I Boková, T Gaemelke, K Novotná, LG Hvid… - Multiple Sclerosis and …, 2024‏ - Elsevier
Objective The aim of the present systematic review was to investigate the effects of voluntary
walking interventions in persons with multiple sclerosis (pwMS). For this purpose, we …

Consensus based framework for digital mobility monitoring

F Kluge, S Del Din, A Cereatti, H Gaßner, C Hansen… - PloS one, 2021‏ - journals.plos.org
Digital mobility assessment using wearable sensor systems has the potential to capture
walking performance in a patient's natural environment. It enables monitoring of health …

Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a sco** review

AM Polhemus, R Bergquist, MB de Basea, G Brittain… - BMJ open, 2020‏ - bmjopen.bmj.com
Introduction Advances in wearable sensor technology now enable frequent, objective
monitoring of real-world walking. Walking-related digital mobility outcomes (DMOs), such as …

Global, regional and national quality of life in patients with multiple sclerosis: a global systematic review and meta-analysis

FP Kan, Z Hoseinipalangi, N Ahmadi… - BMJ supportive & …, 2022‏ - spcare.bmj.com
Background and aim The purpose of this study was to evaluate the health-related quality of
life (HRQOL) of patients with multiple sclerosis (MS) globally to provide precise information …

Performed and perceived walking ability in relation to the Expanded Disability Status Scale in persons with multiple sclerosis

D Langeskov-Christensen, P Feys, I Baert… - Journal of the …, 2017‏ - Elsevier
Background The severity of walking impairment in persons with multiple sclerosis (pwMS) at
different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is …