Biological sequence classification: A review on data and general methods

C Ao, S Jiao, Y Wang, L Yu, Q Zou - Research, 2022 - spj.science.org
With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …

Bioactive milk peptides: An updated comprehensive overview and database

SDH Nielsen, N Liang, H Rathish, BJ Kim… - Critical Reviews in …, 2024 - Taylor & Francis
Partial digestion of milk proteins leads to the formation of numerous bioactive peptides.
Previously, our research team thoroughly examined the decades of existing literature on …

SBSM-Pro: support bio-sequence machine for proteins

Y Wang, Y Zhai, Y Ding, Q Zou - Science China Information Sciences, 2024 - Springer
Proteins play a pivotal role in biological systems. The use of machine learning algorithms for
protein classification can assist and even guide biological experiments, offering crucial …

POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability

F Li, Y Zhou, Y Zhang, J Yin, Y Qiu… - Briefings in …, 2022 - academic.oup.com
Mass spectrometry-based proteomic technique has become indispensable in current
exploration of complex and dynamic biological processes. Instrument development has …

Identifying SNARE proteins using an alignment-free method based on multiscan convolutional neural network and PSSM profiles

QH Kha, QT Ho, NQK Le - Journal of Chemical Information and …, 2022 - ACS Publications
Background: SNARE proteins play a vital role in membrane fusion and cellular physiology
and pathological processes. Many potential therapeutics for mental diseases or even cancer …

MRMD2. 0: a python tool for machine learning with feature ranking and reduction

S He, F Guo, Q Zou - Current Bioinformatics, 2020 - ingentaconnect.com
Aims: The study aims to find a way to reduce the dimensionality of the dataset. Background:
Dimensionality reduction is the key issue of the machine learning process. It does not only …

Improving protein-protein interactions prediction accuracy using XGBoost feature selection and stacked ensemble classifier

C Chen, Q Zhang, B Yu, Z Yu, PJ Lawrence… - Computers in biology …, 2020 - Elsevier
Protein-protein interactions (PPIs) are involved with most cellular activities at the proteomic
level, making the study of PPIs necessary to comprehending any biological process …

PAtbP-EnC: Identifying anti-tubercular peptides using multi-feature representation and genetic algorithm-based deep ensemble model

S Akbar, A Raza, T Al Shloul, A Ahmad, A Saeed… - IEEE …, 2023 - ieeexplore.ieee.org
Mycobacterium tuberculosis, a highly perilous pathogen in humans, serves as the causative
agent of tuberculosis (TB), affecting nearly 33% of the global population. With the increasing …

Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening

S Basith, B Manavalan, T Hwan Shin… - Medicinal research …, 2020 - Wiley Online Library
Discovery and development of biopeptides are time‐consuming, laborious, and dependent
on various factors. Data‐driven computational methods, especially machine learning (ML) …

mCSM-PPI2: predicting the effects of mutations on protein–protein interactions

CHM Rodrigues, Y Myung, DEV Pires… - Nucleic acids …, 2019 - academic.oup.com
Protein–protein Interactions are involved in most fundamental biological processes, with
disease causing mutations enriched at their interfaces. Here we present mCSM-PPI2, a …