Photodynamic therapy is a promising approach for cancer treatment that relies on the
administration of a photosensitizer followed by tumor illumination. The generated oxidative …

Increasing oxidative stress, a major characteristic of aging, has been implicated in a variety
of age-related pathologies. In aging, oxidant production from several sources is increased …

The transcription factor nuclear factor erythroid-derived 2-like 2 (NRF2) participates in the
activation of the antioxidant cytoprotective pathway and other important physiological …

Mitogen-activated protein kinases (MAPKs) mediate a wide variety of cellular behaviors in
response to extracellular stimuli. One of the main subgroups, the p38 MAP kinases, has …

Cap'n'collar (Cnc) transcription factors are conserved in metazoans and have important
developmental and homeostatic functions. The vertebrate Nrf1, Nrf2, and Nrf3; the …

This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological …

Stress-related disorders, such as depression and anxiety, present marked deficits in
behavioral and cognitive functions related to reward. These are highly prevalent disabling …

Photodynamic therapy (PDT) has emerged as a promising alternative to conventional
cancer therapies such as surgery, chemotherapy, and radiotherapy. PDT comprises the …

Abstract Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative
degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in …

Photodynamic therapy (PDT) involves the administration of a photosensitizer (PS) followed
by illumination with visible light, leading to generation of reactive oxygen species. The …