In the past decade, advances in genome sequencing have allowed researchers to uncover
the history of hybridization in diverse groups of species, including our own. Although the …

Epistasis occurs when the effect of a mutation depends on its carrier's genetic background.
Despite increasing evidence that epistasis for fitness is common, its role during evolution is …

Speciation is the process by which barriers to gene flow evolve between populations.
Although we now know that speciation is largely driven by natural selection, knowledge of …

Ecologically mediated selection against hybrids, caused by hybrid phenotypes fitting poorly
into available niches, is typically viewed as distinct from selection caused by epistatic …

By formalizing the relationship between genotype or phenotype and fitness, fitness
landscapes harbor information on molecular and evolutionary constraints. The shape of the …

Many traits of interest are highly heritable and genetically complex, meaning that much of
the variation they exhibit arises from differences at numerous loci in the genome. Complex …

Hybrid incompatibilities occur when interactions between opposite ancestry alleles at
different loci reduce the fitness of hybrids. Most work on incompatibilities has focused on …

The genomic era has made clear that introgression, or the movement of genetic material
between species, is a common feature of evolution. Examples of both adaptive and …

Adaptation often proceeds from standing variation, and natural selection acting on pairs of
populations is a quantitative continuum ranging from parallel to divergent. Yet, it is unclear …

Transmissible cancers, in which cancer cells themselves act as an infectious agent, have
been identified in Tasmanian devils, dogs, and four bivalves. We investigated a …